Konu "Moleküler Biyoloji ve Genetik" için Makale listeleme
Toplam kayıt 10, listelenen: 1-10
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Alterations in Promoter Methylation Status of Tumor Suppressor HIC1, SFRP2, and DAPK1 Genes in Prostate Carcinomas
Hypermethylated genomic DNA is a common feature in tumoral tissues, although the prevalence of this modification remains poorly understood. We aimed to determine the frequency of five tumor suppressor (TS) genes in prostate ... -
Artificial food sweetener aspartame induces stress response in model organism Schizosaccharomyces pombe
Aspartame (APM) is a non-nutritive artificial sweetener that has been widely used in manyproducts since 1981. Molecular studies have found that it alters the expression of tumoursuppressor genes and oncogenes, forms DNA-DNA ... -
INVESTIGATION OF COSMC GENE DNA METHYLATION PROFILE AND EXPRESSION LEVEL IN IGA
Galactosyltransferase core-1 beta3-galactosyltransferase-1 (C1GALT1) and core 1 3-galactosyltransferase-specific molecular chaperone (COSMC) are required for the O-glycosylation of the IgA1 hinge region. IgA nephropathy ... -
Mutational landscape of severe combined immunodeficiency patients from Turkey.
Severe combined immunodeficiency (SCID) has a diverse genetic aetiology, where a clinical phenotype, caused by single and/or multiple gene variants, can give rise to multiple presentations. The advent of next-generation ... -
NOONAN SENDROMU’NUN PRENATAL TANISINDA PTPN11 GEN ANALİZLERİNİN ETKİNLİĞİ
(2021)Amaç: Hücre büyüme, farklılaşma, yaşlanma ve siklus düzenlenmesindeönemli rol oynayan RAS-MAPK (Rat-sarcoma-Mitogen-activated-protein-kinase) yolağında bulunan 29 gendeki dominantpatojenik varyantların yol açtığı klinik ... -
Pre-transplantation and post-transplantation serum Bone Alkaline Phosphatase levels in renal transplant patients
(2014)© 2014 OMU.Bone Alkaline Phosphatase (BAP) reflects the biosynthetic activity of the osteoblasts. End-stage renal disease and renal transplantation have effects on bone metabolism. The aim of this study was to evaluate ... -
Prevalence of known mutations in the MEFV gene in a population screening with high rate of carriers
The Familial Mediterranean Fever (FMF) shows an autosomal recessive pattern of inheritance and affects certain ethnic groups. Disease is caused by mutations in MEFV gene and more than 180 mutations have been defined in ... -
Soluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study
Introduction. All findings of preeclampsia appear as the clinical consequences of diffuse endothelial dysfunction. Soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) was recently introduced as a TNF ...