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dc.contributor.authorCansiz, H
dc.contributor.authorOzturk, O
dc.contributor.authorKarakullukcu, B
dc.contributor.authorOzek, H
dc.date.accessioned2021-03-02T22:57:21Z
dc.date.available2021-03-02T22:57:21Z
dc.date.issued2001
dc.identifier.citationOzturk O., Ozek H., Cansiz H., Karakullukcu B., "Primary malignant melanoma of the pharynx", JOURNAL OF LARYNGOLOGY AND OTOLOGY, cilt.115, sa.11, ss.931-934, 2001
dc.identifier.issn0022-2151
dc.identifier.otherav_0f9c9d39-174b-4a61-ae89-a15176ca8493
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/16031
dc.identifier.urihttps://doi.org/10.1258/0022215011909404
dc.description.abstractPrimary mucosal malignant melanomas are rare. They appear late in life and their prognosis is grave. Although there is no consensus on therapy, wide surgical resection followed by radiotherapy, chemotherapy and immunotherapy are treatment modalities. In this report we present a case of widespread primary mucosal malignant melanoma located in the pharynx. After immunotherapy (four cycles of interleukin-2 and interferon-alpha) and chemotherapy (four cycles of cisplatin and dacarbazine) has been applied as primary therapy for suppression of the mass, transoral total pharyngeal resection was performed. After surgery three cycles of immunotherapy and three cycles of chemotherapy were administered followed by radiotherapy (total dose of 6600 cGy). An additional three cycles of immunotherapy and chemotherapy were administered. Although no local recurrence was observed during the 14 months of follow-up after the completion of radiotherapy, cranial and lung metastasis were detected in the 12th month.
dc.language.isoeng
dc.subjectKulak Burun Boğaz
dc.subjectCerrahi Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKULAK BURUN BOĞAZ
dc.titlePrimary malignant melanoma of the pharynx
dc.typeMakale
dc.relation.journalJOURNAL OF LARYNGOLOGY AND OTOLOGY
dc.contributor.department, ,
dc.identifier.volume115
dc.identifier.issue11
dc.identifier.startpage931
dc.identifier.endpage934
dc.contributor.firstauthorID65612


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