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dc.contributor.authorÇelik, Ayça İribaş
dc.contributor.authorBayramoğlu, Zuhal
dc.contributor.authorKılıç, Suar Çakı
dc.contributor.authorKarakaş, Zeynep
dc.contributor.authorÜnüvar, Ayşegül
dc.contributor.authorTuna, Rumeysa
dc.contributor.authorKaraman, Serap
dc.contributor.authorOktar, Tayfun
dc.contributor.authorAnak, Sema
dc.contributor.authorDoğan, Öner
dc.contributor.authorTuğcu, Deniz
dc.date.accessioned2022-07-04T12:56:46Z
dc.date.available2022-07-04T12:56:46Z
dc.date.issued2022
dc.identifier.citationTuna R., Karaman S., Oktar T., Anak S., Doğan Ö., Ünüvar A., Tuğcu D., Bayramoğlu Z., Kılıç S. Ç. , Çelik A. İ. , et al., "Bladder granulocytic sarcoma in a child: case report and literature review", Turkish Journal of Pediatrics, cilt.64, sa.1, ss.152-159, 2022
dc.identifier.issn0041-4301
dc.identifier.otherav_330ce91c-69c2-4700-a7d5-314636034ac9
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/182220
dc.identifier.urihttps://doi.org/10.24953/turkjped.2020.275
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/330ce91c-69c2-4700-a7d5-314636034ac9/file
dc.description.abstract© 2022, Turkish National Pediatric Society. All rights reserved.Background. Granulocytic sarcoma (GS) is an extramedullary solid tumor composed of immature myeloid cells. GS has been associated with acute myeloid leukemia (AML), myelodysplastic syndromes or myeloproliferative diseases. Although GS can affect various tissues of the human body, it has rarely been reported in other soft tissues such as the breast, gastrointestinal, respiratory and genitourinary tracts. We report a pediatric case diagnosed with granulocytic sarcoma of the bladder and concomitant AML. Case. A twelve-year-old previously healthy girl was admitted to the pediatric urology clinic with a ten-day history of hematuria and pollakiuria. Laboratory examinations revealed anemia, thrombocytopenia and neutrophilic leukocytosis. Bone marrow aspiration results were consistent with acute myeloid leukemia-FAB subtype M2-. Abdominal magnetic resonance imaging (MRI) showed an irregularly bounded 12 cm mass on the right side of the bladder. Transurethral resection (TUR) pathology was consistent with granulocytic sarcoma. After a multimodal treatment approach, complete remission was achieved. Conclusions. Malignant bladder masses are rare causes of macroscopic hematuria in childhood. The diagnostic spectrum is wide, ranging from rhabdomyosarcoma to leukemia involvement. The bladder is a rare site of extramedullary involvement in pediatric patients with AML. Multimodal treatment should be considered on a per-patient basis.
dc.language.isoeng
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectPediatrics, Perinatology and Child Health
dc.subjectHealth Sciences
dc.subjectPEDİATRİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectSağlık Bilimleri
dc.titleBladder granulocytic sarcoma in a child: case report and literature review
dc.typeMakale
dc.relation.journalTurkish Journal of Pediatrics
dc.contributor.departmentİstanbul Tıp Fakültesi , ,
dc.identifier.volume64
dc.identifier.issue1
dc.identifier.startpage152
dc.identifier.endpage159
dc.contributor.firstauthorID3422036


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