Show simple item record

dc.contributor.authorÖksüzömer, Mehmet Ali Faruk
dc.contributor.authorYalçıntepe Güneştutar, Leman
dc.contributor.authorErdag, Demet
dc.contributor.authorKoç, Serkan Naci
dc.date.accessioned2022-07-04T14:13:56Z
dc.date.available2022-07-04T14:13:56Z
dc.date.issued2022
dc.identifier.citationErdag D., Koç S. N. , Öksüzömer M. A. F. , Yalçıntepe Güneştutar L., "Synergistic effect of selenium and genipin triggers viability of 3T3 cells on PVA/Gelatin scaffolds", Acta Bioeng Biomech, cilt.24, sa.1, ss.179-190, 2022
dc.identifier.issn1509-409X
dc.identifier.othervv_1032021
dc.identifier.otherav_6e0cf8f2-36ba-4213-8ea9-c55edc0c4c69
dc.identifier.urihttp://hdl.handle.net/20.500.12627/183218
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/6e0cf8f2-36ba-4213-8ea9-c55edc0c4c69/file
dc.identifier.urihttps://doi.org/10.37190/abb-01944-2021-04
dc.description.abstractPurpose: The aim of this study was to reveal the first time synergistic effect of GP and selenium (Se) on 3T3 cells seeded on natural and non-cytotoxic porous scaffolds with poly(vinyl alcohol) (PVA) and gelatin (GE). Methods: Electrospinning scaffolds were produced as PVA/GE/GA crosslinked with glutaraldehyde (GA) and freeze/dried scaffolds crosslinked with genipin (GP) were divided into two groups as PVA/GE/GP5 and PVA/GE/GP8. The scaffolds were investigated in terms of pore morphology, swell ratio, biodegradation, and biocompatibility. The biocompatibility of the material was tested in vitro by MTT assay on 1, 2, and 3 days to test the cell viability of 3T3 cells. Results: It was observed that Se triggered the excellent cell growth and proliferation on electrospinning and freeze drying PVA/GE scaffolds. Conclusions: Selenium with PVA/GE scaffolds can be a promising candidate for wound healing application, as it significantly increases cell viability on scaffolds. It is thought that the synergistic effect of selenium with genipin may be an important step in tissue engineering applications. The preliminary study can be supported by in vivo studies in the future.
dc.language.isoeng
dc.subjectBiyomekanik
dc.subjectDiğer
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectMultidisciplinary
dc.subjectBiophysics
dc.subjectChemistry (miscellaneous)
dc.subjectBiomedical Engineering
dc.subjectGeneral Chemistry
dc.subjectBioengineering
dc.subjectFamily Practice
dc.subjectFundamentals and Skills
dc.subjectGeneral Health Professions
dc.subjectPathophysiology
dc.subjectInternal Medicine
dc.subjectMedicine (miscellaneous)
dc.subjectGeneral Medicine
dc.subjectPhysical Sciences
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectBiyoloji ve Biyokimya
dc.subjectAssessment and Diagnosis
dc.subjectKlinik Tıp (MED)
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectTemel Bilimler (SCI)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKlinik Tıp
dc.subjectMühendislik
dc.subjectDoğa Bilimleri Genel
dc.subjectKimya
dc.subjectTIP, GENEL & İÇECEK
dc.subjectMÜHENDİSLİK, BİYOMEDİKSEL
dc.subjectÇOK DİSİPLİNLİ BİLİMLER
dc.subjectBİYOFİZİK
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyofizik
dc.subjectBiyomedikal Mühendisliği
dc.titleSynergistic effect of selenium and genipin triggers viability of 3T3 cells on PVA/Gelatin scaffolds
dc.typeMakale
dc.relation.journalActa Bioeng Biomech
dc.contributor.departmentBiruni Üniversitesi , Meslek Yüksekokulu , Bilgisayar Teknolojileri Bölümü
dc.identifier.volume24
dc.identifier.issue1
dc.identifier.startpage179
dc.identifier.endpage190
dc.contributor.firstauthorID3431167


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record