dc.contributor.author | Genc, Omer | |
dc.contributor.author | Sahin, Irfan | |
dc.contributor.author | Alici, Gokhan | |
dc.contributor.author | BARMAN, HASAN ALİ | |
dc.contributor.author | ATICI, ADEM | |
dc.contributor.author | Tugrul, Sevil | |
dc.date.accessioned | 2022-07-04T15:49:28Z | |
dc.date.available | 2022-07-04T15:49:28Z | |
dc.identifier.citation | Alici G., BARMAN H. A. , ATICI A., Tugrul S., Genc O., Sahin I., "<p>The Impact of Lesion Complexity and the CHA(2)DS(2)-VASc Score on Spontaneous Reperfusion in Patients with ST-Segment Elevation Myocardial Infarction</p>", INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, cilt.2022, 2022 | |
dc.identifier.issn | 1368-5031 | |
dc.identifier.other | av_c4aa1b50-123f-4aa2-815c-d9444de3fc2f | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/184591 | |
dc.identifier.uri | https://avesis.istanbul.edu.tr/api/publication/c4aa1b50-123f-4aa2-815c-d9444de3fc2f/file | |
dc.identifier.uri | https://doi.org/10.1155/2022/8066780 | |
dc.description.abstract | Background. In patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI), a patent infarct-related artery (IRA) on initial angiography is defined as spontaneous reperfusion (SR). Objective. The present study aimed to determine the impact of lesion complexity and the CHA(2)DS(2)-VASc score on SR in patients with STEMI. Methods. A total number of 1,641 consecutive patients with STEMI undergoing primary PCI were assessed for this study. Patients were divided into 2 groups, those with SR, SR(+) (n = 239), and those without SR, SR(-) (n = 1402), according to their initial angiography and SR status. CHA(2)DS(2)-VASc scores were calculated for all patients. The lesion complexity of coronary artery disease was assessed with the SYNTAX score. Results. The CHA(2)DS(2)-VASc and SYNTAX scores were significantly lower in the SR(+) group compared to the SR(-) (mean CHA(2)DS(2)-VASc, 1.36 +/- 0.64 vs. 2.01 +/- 0.80, p < 0.001; mean SYNTAX score, 15.51 +/-& nbsp;5.94 vs. 17.08 +/-& nbsp;8.29, p < 0.001). After the multivariate regression analysis, a lower CHA(2)DS(2)-VASc (OR = 0.288, p < 0.001), SYNTAX score (OR = 0.920, p=0.007), uric acid (OR = 0.868, p=0.005), CRP (OR = 0.939, p=0.001), BNP (OR = 0.998, p=0.004), and troponin (OR = 0.991, p=0.001) were independent predictors of SR. In-hospital mortality rates were significantly lower in the SR(+) group compared to the SR(-) (0% vs. 6.7%, p < 0.001). Conclusion. Our study demonstrated that lesion complexity and the CHA(2)DS(2)-VASc score are independently associated with spontaneous reperfusion. | |
dc.language.iso | eng | |
dc.subject | Fundamentals and Skills | |
dc.subject | General Health Professions | |
dc.subject | Pathophysiology | |
dc.subject | Pharmacy | |
dc.subject | Assessment and Diagnosis | |
dc.subject | Medicine (miscellaneous) | |
dc.subject | General Medicine | |
dc.subject | Drug Guides | |
dc.subject | Life Sciences | |
dc.subject | Health Sciences | |
dc.subject | Internal Medicine | |
dc.subject | TIP, GENEL & İÇECEK | |
dc.subject | Klinik Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | FARMAKOLOJİ VE ECZACILIK | |
dc.subject | Farmakoloji ve Toksikoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Temel Tıp Bilimleri | |
dc.subject | Eczacılık | |
dc.subject | Temel Eczacılık Bilimleri | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Pharmacology | |
dc.subject | General Pharmacology, Toxicology and Pharmaceutics | |
dc.subject | Pharmacology, Toxicology and Pharmaceutics (miscellaneous) | |
dc.subject | Family Practice | |
dc.subject | Pharmacology (medical) | |
dc.title | <p>The Impact of Lesion Complexity and the CHA(2)DS(2)-VASc Score on Spontaneous Reperfusion in Patients with ST-Segment Elevation Myocardial Infarction</p> | |
dc.type | Makale | |
dc.relation.journal | INTERNATIONAL JOURNAL OF CLINICAL PRACTICE | |
dc.contributor.department | Okmeydani Training & Res Hosp , , | |
dc.identifier.volume | 2022 | |
dc.contributor.firstauthorID | 3405484 | |