SET oncogene is upregulated in pediatric acute lymphoblastic leukemia

Date
2012
Author
Emrence, Zeliha
Akbiyik, Meral
Agaoglu, Leyla
Unuvar, Aysegul
Ozbek, Ugur
Abaci, Neslihan
Karakas, Zeynep
Grosveld, Gerard
Kandilci, Ayten
Ekmekci, Sema Sirma
Ekmekci, Cumhur G.
Ustek, Duran
Devecioglu, Omer
Gulec, Cagri
Metadata
Show full item record
Abstract
Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive cell lines, patient-derived chronic myeloid leukemia CD34-positive cells, and some solid tumors.
URI
http://hdl.handle.net/20.500.12627/674
Collections