Vitamin E has a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats
Date
2011Author
Tahan, Veysel
Uzun, Hafize
Tahan, Gulgun
Dogusoy, Gulen
Aydin, Seval
Aytac, Erman
Aytekin, Huseyin
GÜNDÜZ, FEYZA
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Background: Increased free radical production, decreased antioxidant capacity and excessive inflammation are well-known features in the pathogenesis of inflammatory bowel disease. Vitamin E is a powerful antioxidant and a scavenger of hydroxyl radicals, and it has been shown to have anti-inflammatory activities in tissues. We investigated the effects of vitamin E on inflammatory activities using an acetic acid (AA)induced ulcerative colitis model in rats.
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