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dc.contributor.authorDEVRIM-UCOK, Muge
dc.contributor.authorUcok, Alp
dc.contributor.authorKESKIN-ERGEN, H. Yasemin
dc.date.accessioned2021-03-05T09:16:16Z
dc.date.available2021-03-05T09:16:16Z
dc.date.issued2006
dc.identifier.citationDEVRIM-UCOK M., KESKIN-ERGEN H. Y. , Ucok A., "Novelty P3 and P3b in first-episode schizophrenia and chronic schizophrenia", PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, cilt.30, ss.1426-1434, 2006
dc.identifier.issn0278-5846
dc.identifier.otherav_9d1e884a-f8fe-4649-b2e0-150e2c9b85a7
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/105549
dc.identifier.urihttps://doi.org/10.1016/j.pnpbp.2006.05.019
dc.description.abstractThe objective of this study was to evaluate P3b and novelty P3 responses in patients with first-episode schizophrenia (FES) and chronic schizophrenia (CS). P3b is consistently reported to be reduced in CS. However, novelty P3 results in CS are controversial. Novelty P3 is not studied, and there are only a few P3b studies in patients with FES. Subject groups comprised 31 patients with FES and 36 younger control subjects, and 26 patients with CS and 35 older control subjects. Automatically elicited auditory novelty P3 and effortfully elicited auditory P3b potentials were assessed. P3b amplitudes were reduced in both patients with FES and CS relative to their controls. CS and FES patients did not differ in P3b amplitude. Novelty P3 amplitude was reduced in patients with CS. Novelty P3 amplitude in patients with FES did not differ from their controls. P3b amplitude reduction may be a trait marker of schizophrenia and may not progress over the course of illness, although this can only be definitively determined by longitudinal studies. Novelty P3 amplitude reduction present in patients with CS, is not found at the onset of illness. Novelty P3 seems unaffected early in the disease process. (c) 2006 Elsevier Inc. All rights reserved.
dc.language.isoeng
dc.subjectPsikiyatri
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectNöroloji
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSinirbilim ve Davranış
dc.subjectNEUROSCIENCES
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.titleNovelty P3 and P3b in first-episode schizophrenia and chronic schizophrenia
dc.typeMakale
dc.relation.journalPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume30
dc.identifier.issue8
dc.identifier.startpage1426
dc.identifier.endpage1434
dc.contributor.firstauthorID37708


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