dc.contributor.author | Celik, AF | |
dc.contributor.author | Acbay, O | |
dc.contributor.author | Gundogdu, S | |
dc.date.accessioned | 2021-03-02T21:29:37Z | |
dc.date.available | 2021-03-02T21:29:37Z | |
dc.date.issued | 1996 | |
dc.identifier.citation | Acbay O., Celik A., Gundogdu S., "Does Helicobacter pylori-induced gastritis enhance food-stimulated insulin release?", DIGESTIVE DISEASES AND SCIENCES, cilt.41, sa.7, ss.1327-1331, 1996 | |
dc.identifier.issn | 0163-2116 | |
dc.identifier.other | av_073f0366-f914-45da-9cbc-0785268a39dc | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/10721 | |
dc.identifier.uri | https://doi.org/10.1007/bf02088555 | |
dc.description.abstract | The fact that H. pylori gastritis results in an increased secretion of basal and meal-stimulated gastrin, which is also a physiologic amplifier of insulin release directed us to investigate whether H, pylori gastritis may lead to an enhancement of nutrient-stimulated insulin secretion. For this purpose, we have investigated the insulin responses to both oral glucose and a mixed meal in 15 patients with H. pylori gastritis before and one month after the eradication therapy and also in 15 H. pylori-negative control subjects. The areas under the curve (AUC) for serum insulin following both oral glucose and a mixed meal in the patients with H, pylori gastritis before the eradication were significantly (P < 0.05) higher than those in the H. pylori-negative controls, After the eradication of H. pylori, the AUC for serum insulin following oral glucose and mixed meal decreased by 9.4% and 13.1%, respectively (P < 0.001 in both), and serum basal and meal-stimulated gastrin levels decreased significantly (P < 0.001). These results suggest that H. pylori gastritis enhances glucose and meal-stimulated insulin release probably by increasing gastrin secretion. | |
dc.language.iso | eng | |
dc.subject | İç Hastalıkları | |
dc.subject | Gastroenteroloji-(Hepatoloji) | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | GASTROENTEROLOJİ VE HEPATOLOJİ | |
dc.title | Does Helicobacter pylori-induced gastritis enhance food-stimulated insulin release? | |
dc.type | Makale | |
dc.relation.journal | DIGESTIVE DISEASES AND SCIENCES | |
dc.contributor.department | , , | |
dc.identifier.volume | 41 | |
dc.identifier.issue | 7 | |
dc.identifier.startpage | 1327 | |
dc.identifier.endpage | 1331 | |
dc.contributor.firstauthorID | 117667 | |