| dc.contributor.author | Kuskucu, Aysegul | |
| dc.contributor.author | Sahin, Fusun | |
| dc.contributor.author | Karaca, Nilgun | |
| dc.contributor.author | Yildiz, Pinar | |
| dc.contributor.author | Kuskucu, Mert Ahmet | |
| dc.contributor.author | Midilli, Kenan | |
| dc.date.accessioned | 2021-03-05T09:56:34Z | |
| dc.date.available | 2021-03-05T09:56:34Z | |
| dc.identifier.citation | Sahin F., Yildiz P., Kuskucu A., Kuskucu M. A. , Karaca N., Midilli K., "The effect of CD14 and TLR4 gene polimorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study", BMC PULMONARY MEDICINE, cilt.14, 2014 | |
| dc.identifier.issn | 1471-2466 | |
| dc.identifier.other | vv_1032021 | |
| dc.identifier.other | av_a0643527-f235-4ced-b273-742f343bc69b | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12627/107588 | |
| dc.identifier.uri | https://doi.org/10.1186/1471-2466-14-20 | |
| dc.description.abstract | Background: Endotoxins stimulate T helper 1 cell maturation and send a negative signal to T helper 2 polarisation. This causes a decrease IgE levels and prevents atopy (Hygiene hypothesis). It is shown that this response is under genetic control by polymorphisms in CD14 and TLR4 genes in some researchs. We aimed to investigate the effects of genetic variants of CD14 (-) and TLR4 (Asp299Gly, Thr399Ile) genes on asthma phenotypes in adults with asthma. | |
| dc.language.iso | eng | |
| dc.subject | Sağlık Bilimleri | |
| dc.subject | Göğüs Hastalıkları ve Allerji | |
| dc.subject | Dahili Tıp Bilimleri | |
| dc.subject | SOLUNUM SİSTEMİ | |
| dc.subject | Klinik Tıp | |
| dc.subject | Klinik Tıp (MED) | |
| dc.subject | Tıp | |
| dc.title | The effect of CD14 and TLR4 gene polimorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study | |
| dc.type | Makale | |
| dc.relation.journal | BMC PULMONARY MEDICINE | |
| dc.contributor.department | Istanbul Yedikule Chest Diseases & Thoracic Surgery Training & Research Hospital , , | |
| dc.identifier.volume | 14 | |
| dc.contributor.firstauthorID | 43357 | |
