Novel N,S- and S,S-substituted dienes synthesized from mercapto triazole and some amine derivatives

Abstract

2-Nitrodiene 1 reacted with 3-mercapto-1,2,4-triazole and cyclohexyl thiol to yield compounds 3 and4, respectively. Compounds 7a-d were obtained by reactions of 6a-d with 2. The novel N,S-substituted dienes 9a-c were obtained by treatment of compound 6b with the piperazine derivatives 8a-c. Compound 6b was reacted with 10 to give compound 11 as a new morpholine derivative. Compound 6b gave a new monobutadienyl homopiperazine 13 when reacted with homopiperazine in methylene chloride. Compound 4 was structurally characterized by single-crystal X-ray diffraction.