dc.contributor.author | Ozel, M | |
dc.contributor.author | Ertas, IE | |
dc.contributor.author | Kahyaoglu, S | |
dc.contributor.author | Sut, N | |
dc.contributor.author | Danisman, N | |
dc.contributor.author | Yilmaz, B | |
dc.contributor.author | Kelekci, S | |
dc.date.accessioned | 2021-03-05T10:39:26Z | |
dc.date.available | 2021-03-05T10:39:26Z | |
dc.date.issued | 2005 | |
dc.identifier.citation | Yilmaz B., Kelekci S., Ertas I., Kahyaoglu S., Ozel M., Sut N., Danisman N., "Misoprostol moistened with acetic acid or saline for second trimester pregnancy termination: a randomized prospective double-blind trial", HUMAN REPRODUCTION, cilt.20, ss.3067-3071, 2005 | |
dc.identifier.issn | 0268-1161 | |
dc.identifier.other | av_a4422f06-ca06-4514-8255-0c416166ffb3 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/109900 | |
dc.identifier.uri | https://doi.org/10.1093/humrep/dei204 | |
dc.description.abstract | BACKGROUND: This study was conducted to evaluate the efficacy and side effects of a new regimen of 800 mu g misoprostol administered intravaginally every 6 h up to a maximum of three doses in 24 h for second trimester pregnancy termination. METHODS: A total of 66 women seeking termination of second trimester pregnancy (30 fetal structural anomaly, six chromosomal abnormality and 30 fetal death) were randomly assigned to one of two treatment groups: (i) intravaginal misoprostol moistened with 3 ml of 5% acetic acid in group A (n = 33); or (ii) intravaginal misoprostol moistened with 3 ml of saline in group B (n = 33). RESULTS: The overall median (range) induction-abortion interval was 10 h (2-46) [10 h (4-35) in 36 live fetuses and 9 h (2-46) in 30 dead fetuses, P = 0.515]. All of the patients in both groups aborted within 48 h (100% success rate). The median (range) induction-abortion interval revealed a significantly faster delivery time (P < 0.001) in group A [8 h (2-24)] than in group B [14 h (3-46)]. CONCLUSIONS: This new regimen of 800 mu g of vaginal misoprostol every 6 h for a maximum of three doses in 24 h was an effective alternative method for second trimester abortion. In addition, misoprostol moistened with acetic acid was significantly more effective than misoprostol moistened with saline. | |
dc.language.iso | eng | |
dc.subject | Biyoloji ve Biyokimya | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Temel Tıp Bilimleri | |
dc.subject | Biyokimya | |
dc.subject | Cerrahi Tıp Bilimleri | |
dc.subject | Kadın Hastalıkları ve Doğum | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | KADIN HASTALIKLARI & DOĞUM | |
dc.subject | ÜREME BİYOLOJİSİ | |
dc.title | Misoprostol moistened with acetic acid or saline for second trimester pregnancy termination: a randomized prospective double-blind trial | |
dc.type | Makale | |
dc.relation.journal | HUMAN REPRODUCTION | |
dc.contributor.department | , , | |
dc.identifier.volume | 20 | |
dc.identifier.issue | 11 | |
dc.identifier.startpage | 3067 | |
dc.identifier.endpage | 3071 | |
dc.contributor.firstauthorID | 176662 | |