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A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients

dc.contributor.authorSpapen, Herbert
dc.contributor.authorDugernier, Thierry
dc.contributor.authorLaterre, Pierre-Francois
dc.contributor.authorDepuydt, Pieter
dc.contributor.authorVincent, Jean-Louis
dc.contributor.authorBogar, Lajos
dc.contributor.authorSzabo, Zsuzsanna
dc.contributor.authorVolgyes, Barbara
dc.contributor.authorManez, Rafael
dc.contributor.authorRAMAZANOĞLU, ATİLLA
dc.contributor.authorTOPELİ İSKİT, ARZU
dc.contributor.authorMastruzzo, Maria A.
dc.contributor.authorJasovich, Abel
dc.contributor.authorRemolif, Christian G.
dc.contributor.authordel Carmen Soria, Liliana
dc.contributor.authorAndresen Hernandez, Max A.
dc.contributor.authorRuiz Balart, Carolina
dc.contributor.authorKremer, Ildiko
dc.contributor.authorMolnar, Zsolt
dc.contributor.authorvon Sonnenburg, Frank
dc.contributor.authorLyons, Arthur
dc.contributor.authorJoannidis, Michael
dc.contributor.authorWelte, Tobias
dc.contributor.authorKlingler, Anton
dc.contributor.authorHochreiter, Romana
dc.contributor.authorWestritschnig, Kerstin
dc.contributor.authorCakar, Nahit
dc.contributor.authorBurgmann, Heinz
dc.contributor.authorRello, Jordi
dc.contributor.authorKrenn, Claus-Georg
dc.contributor.authorLocker, Gottfried
dc.contributor.authorPilger, Ernst
dc.contributor.authorMadl, Christian
dc.contributor.authorBalica, Laura
dc.date.accessioned2021-03-05T10:55:33Z
dc.date.available2021-03-05T10:55:33Z
dc.identifier.citationRello J., Krenn C., Locker G., Pilger E., Madl C., Balica L., Dugernier T., Laterre P., Spapen H., Depuydt P., et al., "A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients", CRITICAL CARE, cilt.21, 2017
dc.identifier.issn1466-609X
dc.identifier.othervv_1032021
dc.identifier.otherav_a59aaa48-e743-441e-a9c1-ff63969946c7
dc.identifier.urihttp://hdl.handle.net/20.500.12627/110760
dc.identifier.urihttps://doi.org/10.1186/s13054-017-1601-9
dc.description.abstractBackground: Currently, no vaccine against Pseudomonas is available. IC43 is a new, recombinant, protein (OprF/I)-based vaccine against the opportunistic pathogen, Pseudomonas aeruginosa, a major cause of serious hospital-acquired infections. IC43 has proven immunogenicity and tolerability in healthy volunteers, patients with burns, and patients with chronic lung diseases. In order to assess the immunogenicity and safety of IC43 in patients who are most at risk of acquiring Pseudomonas infections, it was evaluated in mechanically ventilated ICU patients.
dc.language.isoeng
dc.subjectTıp
dc.subjectİç Hastalıkları
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectKlinik Tıp (MED)
dc.subjectYOĞUN BAKIM
dc.subjectKlinik Tıp
dc.subjectYoğun Bakım
dc.titleA randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients
dc.typeMakale
dc.relation.journalCRITICAL CARE
dc.contributor.departmentMedical University of Vienna , ,
dc.identifier.volume21
dc.contributor.firstauthorID240778


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