dc.contributor.author | Gur, Emel | |
dc.contributor.author | Can, Günay | |
dc.contributor.author | Arvas, Ahmet | |
dc.contributor.author | Aydin, Ali | |
dc.contributor.author | Erener-Ercan, Tugba | |
dc.date.accessioned | 2021-03-05T10:55:47Z | |
dc.date.available | 2021-03-05T10:55:47Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Aydin A., Gur E., Erener-Ercan T., Can G., Arvas A., "Comparison of Different Iron Preparations in the Prophylaxis of Iron-deficiency Anemia", JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.39, ss.495-499, 2017 | |
dc.identifier.issn | 1077-4114 | |
dc.identifier.other | av_a59f4db0-78ca-4d09-b04d-48167d6a4542 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/110776 | |
dc.identifier.uri | https://doi.org/10.1097/mph.0000000000000967 | |
dc.description.abstract | We compared the efficacy of ferrous sulfate (divalent) and ferric polymaltose (trivalent) compounds for the prophylaxis of iron-deficiency anemia (IDA). Study infants included exclusively breast milk-fed term infants. Subjects were divided randomly into 2 groups at 4 months of age and group 1 (n=56) received divalent and group 2 (n=56) received trivalent iron (Fe) preparation at a dose of 2 mg/kg/d for 5 months. At 9 months of age, after a 5-month prophylaxis, a significant increase was observed in hemoglobin (Hb), hematocrit, serum Fe levels, and transferrin saturation in both groups. However, group 1 had significantly higher Hb, hematocrit, mean corpuscular volume, Fe, and transferrin saturation than group 2 (11.7 +/- 0.6 g/dL, 34.6% +/- 1.7%, 76.2 +/- 2.9 fL, 55.5 +/- 1.8 mcg, 20.8 +/- 3.9 g/L, respectively in group 1 vs. 11.3 +/- 0.5 g/dL, 33.5% +/- 1.5%, 74.7 +/- 3.2 fL, 42.5 +/- 1.8 mcg, 14.1 +/- 7.5 g/L, respectively in group 2). No significant difference was found in ferritin values between the groups. Fe deficiency was found in 17 (30.3%) of the subjects in group 1, and 23 (41%) of subjects in group 2 whereas 5 (8.9%) subjects had IDA in group 1 and 12 (12%) in group 2 which were insignificant between groups. No significant difference was found with regard to side effects between 2 Fe preparations. Although divalent Fe therapy led to a higher Hb and serum Fe level, both ferrous and ferric Fe preparations were effective for prophylactic use in the prevention of Fe deficiency and IDA with comparable side effects. | |
dc.language.iso | eng | |
dc.subject | Çocuk Sağlığı ve Hastalıkları | |
dc.subject | İç Hastalıkları | |
dc.subject | Hematoloji | |
dc.subject | Onkoloji | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Tıp | |
dc.subject | PEDİATRİ | |
dc.subject | HEMATOLOJİ | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | ONKOLOJİ | |
dc.title | Comparison of Different Iron Preparations in the Prophylaxis of Iron-deficiency Anemia | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | |
dc.contributor.department | , , | |
dc.identifier.volume | 39 | |
dc.identifier.issue | 7 | |
dc.identifier.startpage | 495 | |
dc.identifier.endpage | 499 | |
dc.contributor.firstauthorID | 91173 | |