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dc.contributor.authorIssever, Halim
dc.contributor.authorUnlucerci, Yesim
dc.contributor.authorArseven, Orhan
dc.contributor.authorOkumus, Gulfer
dc.contributor.authorAbaci, Neslihan
dc.contributor.authorTabak, Levent
dc.contributor.authorUenaltuna, Nihan Erginel
dc.contributor.authorDiz-Kucukkaya, Reyhan
dc.contributor.authorKiyan, Esen
dc.date.accessioned2021-03-05T11:52:29Z
dc.date.available2021-03-05T11:52:29Z
dc.date.issued2008
dc.identifier.citationOkumus G., Kiyan E., Arseven O., Tabak L., Diz-Kucukkaya R., Unlucerci Y., Abaci N., Uenaltuna N. E. , Issever H., "Hereditary thrombophilic risk factors and venous thromboembolism in Istanbul, Turkey: The role in different clinical manifestations of venous thromboembolism", CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, cilt.14, ss.168-173, 2008
dc.identifier.issn1076-0296
dc.identifier.othervv_1032021
dc.identifier.otherav_aa526736-dd97-42c9-9734-27fd94d74b24
dc.identifier.urihttp://hdl.handle.net/20.500.12627/113737
dc.identifier.urihttps://doi.org/10.1177/1076029607305620
dc.description.abstractThe aim of this study was to investigate the hereditary thrombophilic risk factors in patients with venous thromboembolism (NIT E) and whether these risk factors play a different role in patients with isolated pulmonary embolism (PE) as compared with patients with deep vein thrombosis (DVT) and patients with PE + DVT. The protein C (PC), protein S, antithrombin activities, homocysteine levels, and factor V Leiden (FVL) G 169 1A and prothrombin G20210A mutations were evaluated in 191 patients with VTE and 191 controls. The prevalence of FVL and PC deficiency were higher in patients (P =.003 and P =.02, respectively). There was no significant difference for the other risk factors. The combination of thrombophilic risk factors was significantly higher in patients with DVT + PE as compared with patients with isolated PE or DVT (P =.04). In conclusion, the most important hereditary risk factors for VTE in this study were the FVL mutation and PC deficiency.
dc.language.isoeng
dc.subjectHematoloji
dc.subjectHematology
dc.subjectHealth Sciences
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectTıp
dc.subjectPERİFERAL VASKÜLER HASTALIĞI
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectHEMATOLOJİ
dc.titleHereditary thrombophilic risk factors and venous thromboembolism in Istanbul, Turkey: The role in different clinical manifestations of venous thromboembolism
dc.typeMakale
dc.relation.journalCLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume14
dc.identifier.issue2
dc.identifier.startpage168
dc.identifier.endpage173
dc.contributor.firstauthorID25539


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