Thymosin alpha 1 attenuates lipid peroxidation and improves fructose-induced steatohepatitis in rats

Abstract

Objectives: The aim of this study was to investigate the effects of thymosin alpha(1) (T alpha(1)) in rats having fructose-induced steatosis. Fructose leads to experimental steatosis in the liver by exerting its effect on some components of the oxidant/antioxidant system, and on several cytokines (interleukin-1 beta, -2, and -6) in blood.