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Predictive value of serum anti-C1q antibody levels in experimental autoimmune myasthenia gravis

dc.contributor.authorMERIGGIOLI, MN
dc.contributor.authorTuzun, Erdem
dc.contributor.authorROWIN, J
dc.contributor.authorCHRISTADOSS, P
dc.contributor.authorSAINI, SS
dc.contributor.authorGHOSH, S
dc.date.accessioned2021-03-05T13:14:54Z
dc.date.available2021-03-05T13:14:54Z
dc.date.issued2006
dc.identifier.citationTuzun E., SAINI S., GHOSH S., ROWIN J., MERIGGIOLI M., CHRISTADOSS P., "Predictive value of serum anti-C1q antibody levels in experimental autoimmune myasthenia gravis", NEUROMUSCULAR DISORDERS, cilt.16, ss.137-143, 2006
dc.identifier.issn0960-8966
dc.identifier.otherav_b14acaa7-dca1-4a21-987e-2dbccf11e087
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/118121
dc.identifier.urihttps://doi.org/10.1016/j.nmd.2005.11.005
dc.description.abstractComponents of the complement cascade and circulating immune complexes play important roles in both experimental autoimmune myasthenia avis and myasthenia gravis in humans. Thus far, no serological factor has been identified to predict the clinical severity of either myasthenia gravis. Upon immunization with acetylcholine receptor, levels of complement factors C1q, C3 and CIC increase with time in sera from C57BL/6 (B6) mice. Both these and plasma samples from myasthenia gravis patients also contain anti-C1q antibodies. The serum levels of anti-C1q antibodies but not C1q, C3 and CIC are significantly correlated with the clinical severity in the experimental myasthenia mice. However, this correlation is not observed in myasthenia gravis patients. (C) 2005 Elsevier B.V. All rights reserved.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectNöroloji
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSinirbilim ve Davranış
dc.subjectNEUROSCIENCES
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.titlePredictive value of serum anti-C1q antibody levels in experimental autoimmune myasthenia gravis
dc.typeMakale
dc.relation.journalNEUROMUSCULAR DISORDERS
dc.contributor.department, ,
dc.identifier.volume16
dc.identifier.issue2
dc.identifier.startpage137
dc.identifier.endpage143
dc.contributor.firstauthorID1780


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