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The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats

dc.contributor.authorTuncdemir, Matem
dc.contributor.authorErturkuner, Salime Pelin
dc.contributor.authorBasar, Murat
dc.contributor.authorSeckin, Ismail
dc.date.accessioned2021-03-02T21:50:04Z
dc.date.available2021-03-02T21:50:04Z
dc.date.issued2014
dc.identifier.citationErturkuner S. P. , Basar M., Tuncdemir M., Seckin I., "The comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats", PHARMACOLOGICAL REPORTS, cilt.66, sa.2, ss.279-287, 2014
dc.identifier.issn1734-1140
dc.identifier.otherav_0923973f-db21-4e52-b8c4-6a9a5dc686a0
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/11959
dc.identifier.urihttps://doi.org/10.1016/j.pharep.2013.09.010
dc.description.abstractBackground: Hyperglycemia and advanced glucose end substance (AGE) are responsible for excessive reactive oxygen species (ROS) production, which causes oxidative stress in diabetes mellitus. Oxidative stress and high blood pressure may cause injury and glomerulosclerosis in the kidney. End-stage kidney failure induced by glomerulosclerosis leads to microalbuminuria (Ma) in diabetic nephropathy. We investigated the effects of an angiotensin converting enzyme inhibitor (ACEI), perindopril, and an antioxidant, catechin, on podocytes and the glomerular mesangial matrix in experimental diabetic nephropathy using ultrastructural visualization and immunohistochemical staining.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectEczacılık
dc.subjectYaşam Bilimleri
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSağlık Bilimleri
dc.subjectTemel Eczacılık Bilimleri
dc.titleThe comparative effects of perindopril and catechin on mesangial matrix and podocytes in the streptozotocin induced diabetic rats
dc.typeMakale
dc.relation.journalPHARMACOLOGICAL REPORTS
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume66
dc.identifier.issue2
dc.identifier.startpage279
dc.identifier.endpage287
dc.contributor.firstauthorID85392


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