Pulmonary function in multiple sclerosis without any respiratory complaints

Abstract

Objectives: Pulmonary complications in severe multiple sclerosis (MS) are often seen secondary to respiratory muscle dysfunction. The development of respiratory muscle dysfunction and its association with disability during the course of MS is unknown. In our study,we investigated the predictive value of respiratory muscle functions and the change in forced vital capacity (Delta forced vital capacity [FVC]; FVC upright - FVC supine) to detect deterioration of respiratory muscle functions in the early phase of MS.