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dc.contributor.authorGultekin, Nazmi
dc.contributor.authorKucukates, Emine
dc.date.accessioned2021-03-05T14:27:29Z
dc.date.available2021-03-05T14:27:29Z
dc.date.issued2013
dc.identifier.citationGultekin N., Kucukates E., "An unusual form of Naxos disease and its improvement by adjuvant low-dose colchicine therapy", ACTA CARDIOLOGICA, cilt.68, ss.433-437, 2013
dc.identifier.issn0001-5385
dc.identifier.otherav_b7369aff-cd7e-45e2-a27d-628150bf0ff1
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/121947
dc.identifier.urihttps://doi.org/10.1080/ac.68.4.2988900
dc.description.abstractWe evaluated a female patient with an unusual form of Naxos disease, who presented with central cyanosis and clubbing, simulating congenital heart disease. Adjuvant low-dose colchicine therapy (0.5 mg once daily) showed positive effects and has been continued for six months. Colchicine has anti-inflammatory and anti-fibrotic properties. It inhibits mitosis by disrupting tubulin assembly and enhances cellular apoptosis. Follow-up showed improvement in the patient's clinical status, with a dramatic disappearance of the electrical storm and reductions in cyanosis and palmoplantar hyperkeratosis. Low-dose colchicine may be safe and effective in patients with Naxos disease and may reduce related complications.
dc.language.isoeng
dc.subjectKardiyoloji
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCARDIAC ve CARDIOVASCULAR SİSTEMLER
dc.titleAn unusual form of Naxos disease and its improvement by adjuvant low-dose colchicine therapy
dc.typeMakale
dc.relation.journalACTA CARDIOLOGICA
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume68
dc.identifier.issue4
dc.identifier.startpage433
dc.identifier.endpage437
dc.contributor.firstauthorID27640


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