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dc.contributor.authorGuzeldemirci, Nuray Ulusoy
dc.contributor.authorSatana, Dilek
dc.contributor.authorKucukbasmaci, Omer
dc.date.accessioned2021-03-05T15:03:53Z
dc.date.available2021-03-05T15:03:53Z
dc.date.issued2015
dc.identifier.citationGuzeldemirci N. U. , Satana D., Kucukbasmaci O., "Synthesis and antimicrobial evaluation of some new hydrazone derivatives of 6-(4-nitrophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide", ISTANBUL JOURNAL OF PHARMACY, cilt.45, sa.2, ss.127-138, 2015
dc.identifier.othervv_1032021
dc.identifier.otherav_ba323005-e1ee-4a85-ac1f-fa10609bfc66
dc.identifier.urihttp://hdl.handle.net/20.500.12627/123836
dc.description.abstractIn this study, some novel N2-arylidene/cycloalkylidene-(6-(4-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazides (2a-d) were synthesized from (6-(4-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazide (1). The newly synthesized compounds were characterized by IR, 1H NMR, mass and elemental analysis. Their antibacterial and antifungal activities were evaluated against S. aureus ATCC 29213, P. aeruginosa ATCC 27853, E. coli ATCC 25922, C. albicans ATCC 10231, C. parapsilosis ATCC 22019, C. krusei ATCC 6258, T. mentagrophytes var. erinacei NCPF 375, M. gypseum NCPF 580 and T. tonsurans NCPF 245. N2-Cyclohexylidene-(6-(4-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazide (2c) and N2-(3-methylcyclohexylidene)-(6-(4-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazide (2d) showed the highest antibacterial activity. Particularly 2c showed the highest antifungal activity against tested fungi.
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.titleSynthesis and antimicrobial evaluation of some new hydrazone derivatives of 6-(4-nitrophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide
dc.typeMakale
dc.relation.journalISTANBUL JOURNAL OF PHARMACY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume45
dc.identifier.issue2
dc.identifier.startpage127
dc.identifier.endpage138
dc.contributor.firstauthorID219433


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