Frequency of genetic polymorphism for adrenergic receptor beta and cytochrome p450 2D6 enzyme, and effects on tolerability of beta-blocker therapy in heart failure with reduced ejection fraction patients: The Beta GenTURK study
Date
2016Author
Yucel, Ceyhun
Mutlu, Hasim
Demir, Serafettin
Ergene, Oktay
YILMAZ, MEHMET BİRHAN
ZOGHİ, MEHDİ
KAYA, HAKKI
ÇAVUŞOĞLU, YÜKSEL
Aksakal, Enbiya
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Objective: The present objective was to determine frequency of Arginine389Glycine (Arg389Gly) and Cytochrome p450 2D6*10 (Cyp2D6*10) polymorphism in cases of heart failure-reduced ejection fraction (HFREF), and to evaluate the influence of the polymorphisms in response to beta-blocker (BB) therapy.
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