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Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro

dc.contributor.authorGedikoglu, Gunduz
dc.contributor.authorBilir, Ayhan
dc.contributor.authorDel Maestro, Rolando F.
dc.contributor.authorTuna, Sevilcan
dc.contributor.authorOzcan, Emin
dc.contributor.authorAltinoz, Meric A.
dc.date.accessioned2021-03-05T15:58:03Z
dc.date.available2021-03-05T15:58:03Z
dc.date.issued2006
dc.identifier.citationAltinoz M. A. , Bilir A., Del Maestro R. F. , Tuna S., Ozcan E., Gedikoglu G., "Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro", SURGICAL NEUROLOGY, cilt.65, ss.478-485, 2006
dc.identifier.issn0090-3019
dc.identifier.othervv_1032021
dc.identifier.otherav_be61aac3-4368-4bd4-ad28-76f904ccb651
dc.identifier.urihttp://hdl.handle.net/20.500.12627/126446
dc.identifier.urihttps://doi.org/10.1016/j.surneu.2005.06.024
dc.description.abstractBackground: Radiation therapy after surgical resection is the approved treatment of gliomas, and survival benefits are reported with taxane-based chemotherapy. We investigated whether these regimes could be augmented with blood-brain barrier permeable drugs, N and D. Noscapine is an opioid antitussive, which acts anti cancer via blocking microtubule dynamics. Diltiazem is a calcium channel-blocking cardiac antiarrythmic, which also blocks tumor growth and P-glycoprotein.
dc.language.isoeng
dc.subjectTıp
dc.subjectCERRAHİ
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectNöroloji
dc.subjectCerrahi Tıp Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectKLİNİK NEUROLOJİ
dc.subjectSağlık Bilimleri
dc.titleNoscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro
dc.typeMakale
dc.relation.journalSURGICAL NEUROLOGY
dc.contributor.department, ,
dc.identifier.volume65
dc.identifier.issue5
dc.identifier.startpage478
dc.identifier.endpage485
dc.contributor.firstauthorID178629


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