Browsing Makale by Subject "Life Sciences"

Now showing items 1-12 of 12

    • Design and characterisation of colloidal nanocarriers for enhanced skin delivery of etodolac 

      Kahraman, Emine; GÜNGÖR, Sevgi; Saribey, Güler; ERDAL, Meryem Sedef (2021)
      © 2021 Marmara University Press.The aim of this work was to develop colloidal nanocarriers for skin delivery of etodolac (ETD), which is a non-steroidal anti-inflammatory drug orally used for the management of acute pain ...

    • Distribution of Trace Metals in Street Dusts and Tree Leaves and Their Source Identification in a Mid-Populated Anatolian City 

      Nuhoğlu, Yaşar; Nuhoğlu, Çiğdem; Yazıcı, Mustafa; Kuzu, Sadullah Levent; Osmanlioglu, Ahmet Erdal; Kam, Erol
      © 2020, Springer Science+Business Media, LLC, part of Springer Nature.Sivas is a central Anatolian city in Turkey with mid-population. Due to its geographical structure high air pollution episodes can be observed in the ...

    • Extracellular microRNA signature in chronic kidney disease 

      Shrivastav, Shashi; Scott, Richard; Maxwell, Nirmal; Ozturk, Savaş; Beddhu, Srinivasan; Kopp, Jeffrey B.; Raj, Dominic S.; Muralidharan, Jagdeesan; Ramezani, Ali; Hubal, Monica; Knoblach, Susan; Karandish, Sara (2017)
      MicroRNAs (miRNAs) are noncoding RNAs that regulate posttranscriptional gene expression. In this study we characterized the circulating and urinary miRNA pattern associated with reduced glomerular filtration rate, using ...

    • INVESTIGATION OF COSMC GENE DNA METHYLATION PROFILE AND EXPRESSION LEVEL IN IGA 

      Temurhan, Sonay; Aydin, Filiz; Savran, Fatma; Akgul, Sebahat U.; Kekik, Cigdem; Caliskan, Yasar K.; Cebecı, Egemen; Demir, Erol
      Galactosyltransferase core-1 beta3-galactosyltransferase-1 (C1GALT1) and core 1 3-galactosyltransferase-specific molecular chaperone (COSMC) are required for the O-glycosylation of the IgA1 hinge region. IgA nephropathy ...

    • IS PENTRAXIN-3 STRONGER THAN C-REACTIVE PROTEIN TO DETERMINE INFLAMMATION IN PERITONEAL DIALYSIS PATIENTS? 

      Koldas, M.; Uzun, S.; Doventas, Y.; Sumnu, A.; KAZANCIOĞLU, Rümeyza; Gursu, M.; Ozturk, Savaş; Aydin, Z.; Karadag, S. (2012)
      Pentraxin-3 (PTX-3) is the prototype of long pentraxins and is produced by many tissues and organs including vascular endothelial cells in response to pro-inflammatory signals. It is thought to be an independent indicator ...

    • KRONİK HEPATİT B HASTALARINDA SERUM IL-17 DÜZEYLERİNİN DEĞERLENDİRİLMESİ 

      Çakal, Bülent; Akyüz, Filiz (2021)
      Amaç: Kronik Hepatit B virüs (HBV) enfeksiyonunun doğal seyri ve klinik sonuçları enfekte bireyin immün yanıtları ve viral faktörler ile yakından ilişkilidir. Serum IL-17 düzeyleri ile HBV ilişkili özellikle şiddetli ...

    • NOONAN SENDROMU’NUN PRENATAL TANISINDA PTPN11 GEN ANALİZLERİNİN ETKİNLİĞİ 

      Kalelioğlu, İbrahim Halil; Başaran, Seher; Uyguner, Zehra Oya; Yüksel, Atıl; Has, Recep; Toksoy, Güven; Tepgeç, Fatih; Saraç Sivrikoz, Tuğba; Demir, Selma (2021)
      Amaç: Hücre büyüme, farklılaşma, yaşlanma ve siklus düzenlenmesindeönemli rol oynayan RAS-MAPK (Rat-sarcoma-Mitogen-activated-protein-kinase) yolağında bulunan 29 gendeki dominantpatojenik varyantların yol açtığı klinik ...

    • Pre-transplantation and post-transplantation serum Bone Alkaline Phosphatase levels in renal transplant patients 

      Düz, Muhammed Emin; Akaydin, Mükerrem; Öztürk, Savaş; Sari, Soner; Koldaş, Macit; Gümüş, Alper (2014)
      © 2014 OMU.Bone Alkaline Phosphatase (BAP) reflects the biosynthetic activity of the osteoblasts. End-stage renal disease and renal transplantation have effects on bone metabolism. The aim of this study was to evaluate ...

    • Soluble TNF-Like Weak Inducer of Apoptosis as a New Marker in Preeclampsia: A Pilot Clinical Study 

      Ozturk, Savaş; Yildirim, Zeynep Kayaoglu; Sumnu, Abdullah; Bademler, Neslihan; Kilic, Elif; Sumnu, Gulay; Karadag, Serhat; GÜRSU, Meltem; Ozel, Aysegul; Batmaz, Gonca; ATEŞ, SEDA; Dane, Banu
      Introduction. All findings of preeclampsia appear as the clinical consequences of diffuse endothelial dysfunction. Soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) was recently introduced as a TNF ...

    • Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential 

      Sirin, Nermin Gorkem; Baslo, Sezin Alpaydin; Orhan, Elif Kocasoy; Soysal, Aysun; BASLO, Mehmet Barış; ULUÇ, KAYIHAN (2020)
      Objective: To decompose a part of the nerve action potential (NAP), mainly originating from large-myelinated sensory fibers, from mixed NAPs by using a stimulus with long duration during surface recordings.

    • The right temporal variant of frontotemporal dementia is not genetically sporadic: A case series 

      Barkhof, Frederik; van der Flier, Wiesje M.; Erkoyun, Hulya Ulugut; van der Lee, Sven J.; Nijmeijer, Bas; van Spaendonk, Rosalina; Nelissen, Anne; Scarioni, Marta; Dijkstra, Anke; Samancı, Bedia; GÜRVİT, İbrahim Hakan; Yıldırım, Zerrin; Tepgeç, Fatih; Bilgic, Basar; Rozemuller, Annemieke; Pijnenburg, Yolande; Cohn-Hokke, Petra; Scheltens, Philip (2021)
      © 2021 - IOS Press. All rights reserved.Background: Right temporal variant frontotemporal dementia (rtvFTD) has been generally considered as a right sided variant of semantic variant primary progressive aphasia (svPPA), ...

    • Trakya Üniversitesi Eğitim Fakültesi Kampüsü Çevre Düzenleme Proje Önerisi 

      Atik, Damla; Zülfikar, Halide Candan (2020)
      Üniversiteler evrensel bilgi üretimine ve paylaşımına olanak veren bilimsel ve kültürel kuruluşlardır. Toplumun ve ülkenin bilimsel, teknolojik, kültürel, ekonomik ve sosyal gelişimine katkı sağlamaktadırlar. Üniversite ...