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dc.contributor.authorErginel-Unaltuna, Nihan
dc.contributor.authorKOMURCU, E
dc.date.accessioned2021-03-05T18:06:48Z
dc.date.available2021-03-05T18:06:48Z
dc.date.issued2002
dc.identifier.citationKOMURCU E., Erginel-Unaltuna N., "Platelet glycoprotein Ia 807C/T (Phe224) and 873G/A (Thr246) dimorphisms in Turkey.", American journal of hematology, cilt.69, ss.83-4, 2002
dc.identifier.issn0361-8609
dc.identifier.otherav_c8c2659d-4a34-473e-a5a6-813a4ad94f12
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/133043
dc.identifier.urihttps://doi.org/10.1002/ajh.10029
dc.description.abstractAt sites of vascular injury, the platelet collagen receptor Glycoprotein Ia/IIa (GPIa/IIa) acts as an important mediator of platelet adhesion to fibrillar collagens. Two silent polymorphisms (807C/T and 873G/A) within the glycoprotein Ia gene have been implicated in increased risk of developing thrombosis and myocardial infarction in affected individuals. To provide basis for future studies, we examined the frequency of these GPIa polymorphisms for people in Turkey. We analyzed 118 unrelated individuals for their genotypes of the GPIa gene using a multiplexed allele specific-PCR based method. The allelic frequencies were found to be 34% for 807T/873A and 66% for 807C/873G; the genotypic frequencies were 13% for 807TT/873AA, 44% for 807CT/873GA, and 43% for 807CC/873GG. (C) 2002 Wiley-Liss, Inc.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectHematoloji
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectHEMATOLOJİ
dc.titlePlatelet glycoprotein Ia 807C/T (Phe224) and 873G/A (Thr246) dimorphisms in Turkey.
dc.typeMakale
dc.relation.journalAmerican journal of hematology
dc.contributor.departmentİstanbul Üniversitesi , Deneysel Tıp Araştırma Enstitüsü , Genetik
dc.identifier.volume69
dc.identifier.issue1
dc.identifier.startpage83
dc.identifier.endpage4
dc.contributor.firstauthorID28618


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