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dc.contributor.authorCagatay, Atahan
dc.contributor.authorAKGUL, Baki
dc.contributor.authorAgacfidan, Ali
dc.contributor.authorEraksoy, Haluk
dc.contributor.authorBeka, Hayati
dc.contributor.authorKoksal, Muammer Osman
dc.contributor.authorLUBKE, Nadine
dc.contributor.authorVERHEYEN, Jens
dc.contributor.authorKAISER, Rolf
dc.date.accessioned2021-03-05T18:11:59Z
dc.date.available2021-03-05T18:11:59Z
dc.date.issued2015
dc.identifier.citationKoksal M. O. , Beka H., LUBKE N., VERHEYEN J., Eraksoy H., Cagatay A., KAISER R., AKGUL B., Agacfidan A., "HIV-1 subtypes and drug resistance profiles in a cohort of heterosexual patients in Istanbul, Turkey", MEDICAL MICROBIOLOGY AND IMMUNOLOGY, cilt.204, ss.551-555, 2015
dc.identifier.issn0300-8584
dc.identifier.othervv_1032021
dc.identifier.otherav_c92d9824-a078-48d5-bd8c-93ca44eeff30
dc.identifier.urihttp://hdl.handle.net/20.500.12627/133305
dc.identifier.urihttps://doi.org/10.1007/s00430-015-0419-9
dc.description.abstractTurkey is seeing a steady rise in rates of HIV infection in the country. The number of individuals with HIV/AIDS was greater than 7000 in 2014 according to data released by the Ministry of Health, and heterosexual contacts were reported to be the main transmission routes. Istanbul has the highest number of reported cases of HIV infection. The aim of the study was to determine the prevalence of HIV-1 drug resistance in 50 heterosexual patients from Istanbul. The most prevalent subtype was found to be subtype B (56.2 %). Resistance-associated mutations were found in 14 patients with 6/14 patients being therapy-experienced and 8/14 therapy naive at the time point of analysis. With increasing number of patients who require treatment and the rapid up-scaling of the antiretroviral therapy in Turkey, HIV-1 drug resistance testing is recommended before starting treatment in order to achieve better clinical outcomes.
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectİmmünoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMikrobiyoloji
dc.subjectTemel Bilimler
dc.titleHIV-1 subtypes and drug resistance profiles in a cohort of heterosexual patients in Istanbul, Turkey
dc.typeMakale
dc.relation.journalMEDICAL MICROBIOLOGY AND IMMUNOLOGY
dc.contributor.departmentUniversity of Cologne , ,
dc.identifier.volume204
dc.identifier.issue4
dc.identifier.startpage551
dc.identifier.endpage555
dc.contributor.firstauthorID67777


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