Selective molecular biomarkers to predict biologic behavior in pituitary tumors
Date
2017Author
Sav, Aydin
Kovacs, Kalman
Rotondo, Fabio
Syro, Luis V.
Altinoz, Meric A.
Metadata
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Introduction: To date, several cell proliferation markers, apoptosis, vascular markers, oncogenes, tumor suppressor genes, cell cycle mediators, microRNA (miRNAs), and long noncoding RNAs (IncRNAs) have been identified to be involved in the tumorigenesis, migration, proliferation and invasiveness of pituitary adenomas. There are still no reliable morphologic markers predictive of pituitary adenoma recurrence. Recent scientific research introduced new techniques to enable us to attain new information on the genesis and biologic behavior of pituitary adenomas.
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