Peripheral Blood Lymphocyte Activation and RANTES Levels in Asthma
Date
2008Author
Muesellim, Benan
Gemicioglu, Bilun
Deniz, Guennur
Erten, Gaye
Tutluoglu, Buelent
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Aim: Bronchial mucosal inflammation is one of the major characteristics of atopic asthma. Th2 activation and the related cytokine profile, eosinophil activation and infiltration play the main role in the pathogenesis of atopic asthma. The aim of this study was to demonstrate the activation and RANTES (regulated on activation, normal T-cell expressed and presumably secreted) expression of peripheral blood lymphocytes of non-atopic and atopic asthmatic patients.
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