Evaluation of Serum Paraoxonase and Arylesterase Activities in Subjects with Asthma and Chronic Obstructive Lung Disease

Abstract

Background: Asthma and chronic obstructive lung disease (COPD) are characterised by airway inflammation. Paraoxonase1 (PON1) and arylesterase (AE) enzymes have the ability to protect HDL from oxidation and may have antiatherogenic, antioxidant, and antiinflammatory features. We carried out a study to assess if there is a difference between PON1 and AE activities and biochemical values between asthmatics and COPD patients and if there is a difference between comorbid or pure COPD patients.