| dc.contributor.author | Terzioglu, Nalan | |
| dc.contributor.author | Capan, Gultaze | |
| dc.contributor.author | Salman, Aydin | |
| dc.contributor.author | Guzel, Ozlen | |
| dc.date.accessioned | 2021-03-05T19:47:05Z | |
| dc.date.available | 2021-03-05T19:47:05Z | |
| dc.identifier.citation | Guzel O., Terzioglu N., Capan G., Salman A., "Synthesis and biological evaluation of new 5-methyl-N-(3-oxo-1-thia-4-azaspiro[4.5]-dec-4-yl)-3-phenyl-1H-indole-2-carboxamide derivatives", ARKIVOC, ss.98-110, 2006 | |
| dc.identifier.issn | 1551-7004 | |
| dc.identifier.other | vv_1032021 | |
| dc.identifier.other | av_d0e2a0a8-75ff-46d4-96db-fd7692861b7a | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12627/138091 | |
| dc.identifier.uri | https://doi.org/10.3998/ark.5550190.0007.c12 | |
| dc.description.abstract | A series of new 5-methyl-N-(3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-3-phenyl-1H-indole-2carboxamide-derivatives (2 and 3) was synthesized and characterized by IR, H-1-NMR, HSQC, HMBC, C-13-NMR (APT), APCI mass spectral data and elemental analysis. All synthesized compounds were evaluated for in vitro antituberculosis activity against M. tuberculosis H37Rv. Compound 3c was found to provide the highest (90%) inhibition of mycobacterial growth in the primary screen conducted at 6.25 mu g/mL. | |
| dc.language.iso | eng | |
| dc.subject | Biyoinorganik Kimya | |
| dc.subject | Temel Bilimler | |
| dc.subject | Biyokimya | |
| dc.subject | Temel Bilimler (SCI) | |
| dc.subject | Kimya | |
| dc.subject | KİMYA, ORGANİK | |
| dc.title | Synthesis and biological evaluation of new 5-methyl-N-(3-oxo-1-thia-4-azaspiro[4.5]-dec-4-yl)-3-phenyl-1H-indole-2-carboxamide derivatives | |
| dc.type | Makale | |
| dc.relation.journal | ARKIVOC | |
| dc.contributor.department | , , | |
| dc.identifier.startpage | 98 | |
| dc.identifier.endpage | 110 | |
| dc.contributor.firstauthorID | 4906 | |
