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dc.contributor.authorSultuybek, Gonul Kanigur
dc.contributor.authorOnaran, Ilhan
dc.contributor.authorAydogdu, Pinar
dc.contributor.authorBaykara, Onur
dc.contributor.authorNiyazoglu, Mutlu
dc.contributor.authorDELLAL, Fatma Dilek
dc.contributor.authorTAŞAN, ERTUĞRUL
dc.contributor.authorKoc, Arzuhan
dc.date.accessioned2021-03-05T20:50:08Z
dc.date.available2021-03-05T20:50:08Z
dc.date.issued2014
dc.identifier.citationNiyazoglu M., Baykara O., Koc A., Aydogdu P., Onaran I., DELLAL F. D. , TAŞAN E., Sultuybek G. K. , "Association of PARP-1, NF-kappa B, NF-kappa BIA and IL-6, IL-beta 3 and TNF-alpha with Graves Disease and Graves Ophthalmopathy", GENE, cilt.547, ss.226-232, 2014
dc.identifier.issn0378-1119
dc.identifier.othervv_1032021
dc.identifier.otherav_d60a07d5-58c5-46c9-b3a5-b49c7f2028bd
dc.identifier.urihttp://hdl.handle.net/20.500.12627/141264
dc.identifier.urihttps://doi.org/10.1016/j.gene.2014.06.038
dc.description.abstractBackground: Graves Disease (GD) is an autoimmune disorder affected by an interaction of multiple genes such as Nuclear Factor-kappa B (NF-kappa B), Nuclear Factor-kappa B Inhibitor (NF-kappa BIA), Poly (ADP-ribose) polymerase-1 (PARP-1) and cytokines like Interleukin-1 beta (IL-1 beta), Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-alpha) and mostly accompanied by an ocular disorder, Graves Ophthalmopathy (GO). We hypothesize that there is a relationship between GD, GO, polymorphisms of inflammatory related genes and their association with cytokines, which may play important roles in autoimmune and inflammatory processes.
dc.language.isoeng
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Genetik
dc.subjectYaşam Bilimleri
dc.subjectTıp
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectGENETİK VE HAYAT
dc.titleAssociation of PARP-1, NF-kappa B, NF-kappa BIA and IL-6, IL-beta 3 and TNF-alpha with Graves Disease and Graves Ophthalmopathy
dc.typeMakale
dc.relation.journalGENE
dc.contributor.department, ,
dc.identifier.volume547
dc.identifier.issue2
dc.identifier.startpage226
dc.identifier.endpage232
dc.contributor.firstauthorID77677


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