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Evaluation of Cytotoxicity and Mutagenicity of Wastewater from Istanbul: Data from Hospitals and Advanced Wastewater Treatment Plant

dc.contributor.authorSÜSLEYİCİ, BELGİN
dc.contributor.authorCevik, Mehtap
dc.contributor.authorDARTAN, GÜLER
dc.contributor.authorUlker, Melike
dc.contributor.authorBezci, Kivanc
dc.contributor.authorDeliorman, Gokce
dc.contributor.authorCİNEL, İSMAİL HAKKI
dc.contributor.authorAksu, Burak
dc.contributor.authorKeskin, Yasar
dc.contributor.authorCAN, ZEHRA SEMRA
dc.contributor.authorCagatay, Penbe
dc.contributor.authorLAÇİN, TUNÇ
dc.contributor.authorYurdun, Turkan
dc.date.accessioned2021-03-05T20:58:58Z
dc.date.available2021-03-05T20:58:58Z
dc.date.issued2020
dc.identifier.citationCevik M., DARTAN G., Ulker M., Bezci K., Deliorman G., Cagatay P., LAÇİN T., CİNEL İ. H. , Aksu B., Keskin Y., et al., "Evaluation of Cytotoxicity and Mutagenicity of Wastewater from Istanbul: Data from Hospitals and Advanced Wastewater Treatment Plant", BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, cilt.104, ss.852-857, 2020
dc.identifier.issn0007-4861
dc.identifier.othervv_1032021
dc.identifier.otherav_d6c1dee0-cee7-498b-a241-c80afe82d9ad
dc.identifier.urihttp://hdl.handle.net/20.500.12627/141720
dc.identifier.urihttps://doi.org/10.1007/s00128-020-02853-6
dc.description.abstractWastewater (WW) carry considerable amount of chemicals that could have mutagenic or cytotoxic effect from hospital discharges to aquatic environment. Our objective was to determinate the possible mutagenic and toxic effects of hospital originated WWs and effectiveness of the wastewater treatment plants (WTP) functions. In the study the mutagenic and cytotoxic potential of three hospitals and influent/effluent of a treatment plant WW collected in Istanbul and was examined using AMES, XTT, and lactate dehydrogenase (LDH) assays. Mutagenic effects were detected at both hospital discharges and advanced biological wastewater plant. We observed no cytotoxic effect in fibroblasts for LDH and XTT assays whereas high cytotoxicity for all samples was found in hepatocytes by XTT assay. According to the results even if advanced technology is used for treatment of WW, mutagenic and cytotoxic effects still remain, and the present technologies need to be further improved.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectÇEVRE BİLİMLERİ
dc.subjectÇevre / Ekoloji
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectTOKSİKOLOJİ
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectMeslek Bilimleri
dc.subjectFarmasötik Toksikoloji
dc.subjectTarımsal Bilimler
dc.subjectÇevre Mühendisliği
dc.subjectYaşam Bilimleri
dc.subjectMühendislik ve Teknoloji
dc.titleEvaluation of Cytotoxicity and Mutagenicity of Wastewater from Istanbul: Data from Hospitals and Advanced Wastewater Treatment Plant
dc.typeMakale
dc.relation.journalBULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
dc.contributor.departmentMarmara Üniversitesi , ,
dc.identifier.volume104
dc.identifier.issue6
dc.identifier.startpage852
dc.identifier.endpage857
dc.contributor.firstauthorID2280377


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