Effects of Water Samples in Polyethylene Terephthalate Bottles Stored at Different Conditions on Zebrafish Embryos with Relevance to Endocrine Disrupting Chemical Migration and Adenomatous Polyposis Coli Tumor Suppressor Gene

Abstract

Objective: Polyethylene terephthalate (PET) is a material that is most commonly used for production of clear plastic bottles. Adenomatous polyposis coli (APC) and beta-catenin have been related with cancer. Aim was to investigate the effects of PET bottled water samples that were exposed to sunlight and hot water on zebrafish embryos. Moreover the effects of these water samples on APC knockdown zebrafish embryos were also evaluated.