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dc.contributor.authorMutlu, Tuba
dc.contributor.authorGuven, Mehmet
dc.contributor.authorCelkan, Tiraje
dc.contributor.authorOzdemir, Nihal
dc.contributor.authorBatar, Bahadir
dc.date.accessioned2021-03-05T21:23:36Z
dc.date.available2021-03-05T21:23:36Z
dc.date.issued2018
dc.identifier.citationBatar B., Mutlu T., Ozdemir N., Celkan T., Guven M., "Association of the TLR4 and NOD2 Polymorphisms with Childhood Acute Lymphoblastic Leukemia", BEZMIALEM SCIENCE, cilt.6, ss.119-125, 2018
dc.identifier.otherav_d8aaf832-44db-4722-aa4c-27308a7d1404
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/142956
dc.identifier.urihttps://doi.org/10.14235/bs.2018.1678
dc.description.abstractObjective: Immune activation plays a critical role in the immune response against cancer. Although several genetic factors are established with regard to the development of acute lymphoblastic leukemia (ALL), the role of immunogenic genes in ALL pathogenesis remains elusive. Toll-like receptor (TLR) and nucleotidebinding oligomerifation domain containing protein 2 (NOD2) receptors are essential in immune response. The aim of the study was to investigate the association between TLR4 Asp299Gly, TLR4 Thr399Ile, NOD2 Arg702Trp, NOD2 Gly908Arg, and NOD2 Leu1007fsinsC polymorphisms and the risk of childhood ALL.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectTemel Tıp Bilimleri
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTIP, GENEL & İÇECEK
dc.titleAssociation of the TLR4 and NOD2 Polymorphisms with Childhood Acute Lymphoblastic Leukemia
dc.typeMakale
dc.relation.journalBEZMIALEM SCIENCE
dc.contributor.departmentIstanbul University - Cerrahpasa , ,
dc.identifier.volume6
dc.identifier.issue2
dc.identifier.startpage119
dc.identifier.endpage125
dc.contributor.firstauthorID603595


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