Genetic Variation in NFKB1 Gene Influences Liver Enzyme Levels in Morbidly Obese Women
Tarih
2018Yazar
Yenmis, Guven
Arkan, Hulya
Sultuybek, Gonul Kanigur
TAŞAN, ERTUĞRUL
Soydas, Tugba
Üst veri
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Background: Morbid obesity (MO), characterized by low-grade inflammation, is associated with increased C-reactive protein (CRP). NF-KB is a candidate factor for inflammatory responses in inflammatory diseases such as obesity. The objective of our study was to investigate the relationship between NFKB1 gene variations and the risk of MO in the context of the high/normal level of liver enzymes such as Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), gamma-glutamyl transpeptidase (GGT), and alkaline phosphatase (ALP).
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