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Age-related changes in GM1, GD1a, GT1b components of gangliosides in Wistar albino rats

dc.contributor.authorAYDIN, M
dc.contributor.authorISBIR, TURGAY
dc.contributor.authorYILMAZ, H
dc.contributor.authorAGACHAN, Bedia
dc.contributor.authorCengiz, Salih
dc.date.accessioned2021-03-06T08:31:32Z
dc.date.available2021-03-06T08:31:32Z
dc.date.issued2000
dc.identifier.citationAYDIN M., Cengiz S., AGACHAN B., YILMAZ H., ISBIR T., "Age-related changes in GM1, GD1a, GT1b components of gangliosides in Wistar albino rats", CELL BIOCHEMISTRY AND FUNCTION, cilt.18, sa.1, ss.41-45, 2000
dc.identifier.issn0263-6484
dc.identifier.othervv_1032021
dc.identifier.otherav_e155fcff-5990-4eae-9af8-921d1c7a2111
dc.identifier.urihttp://hdl.handle.net/20.500.12627/148362
dc.description.abstractIn this study, age-related changes of GM1, GD la, GT1b fractions of gangliosides were investigated in whole brain of male Wistar albino rats, Insignificant increases were detected in GM1 values from the third to the 24th month, whereas GD1a and GT1b concentrations of ganglioside in 24-month-old rats decreased significantly as compared to 6-month-old rats. Although there were no significant differences in the GD1a/GT1b ratio of any groups. GM1/GD1a and Gm1/GT1b ratios were significantly increased as compared to 6-month-old rats. The increase in the ratios of gangliosides are not due to an increase of GM1 fractions: they result from a decrease of GD la and GT1b fractions of gangliosides. In conclusion, the concentration of ganglioside decreased with ageing. Copyright (C) 2000 John Wiley gr Sons, Ltd.
dc.language.isoeng
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectHÜCRE BİYOLOJİSİ
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectHistoloji-Embriyoloji
dc.subjectYaşam Bilimleri
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.titleAge-related changes in GM1, GD1a, GT1b components of gangliosides in Wistar albino rats
dc.typeMakale
dc.relation.journalCELL BIOCHEMISTRY AND FUNCTION
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume18
dc.identifier.issue1
dc.identifier.startpage41
dc.identifier.endpage45
dc.contributor.firstauthorID6722


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