dc.contributor.author | Caliskan, Mine | |
dc.contributor.author | Varkal, Muhammet Ali | |
dc.contributor.author | Ozmen, Meral | |
dc.contributor.author | Aydinli, Nur | |
dc.contributor.author | Ekici, Baris | |
dc.contributor.author | Uzunhan, Tugce Aksu | |
dc.date.accessioned | 2021-03-02T22:41:01Z | |
dc.date.available | 2021-03-02T22:41:01Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Varkal M. A. , Uzunhan T. A. , Aydinli N., Ekici B., Caliskan M., Ozmen M., "Pediatric Guillain-Barre syndrome: Indicators for a severe course", ANNALS OF INDIAN ACADEMY OF NEUROLOGY, cilt.18, sa.1, ss.24-28, 2015 | |
dc.identifier.issn | 0972-2327 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_0e080b3c-676c-486d-bb46-d8a4de9da257 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/15026 | |
dc.identifier.uri | https://doi.org/10.4103/0972-2327.144274 | |
dc.description.abstract | Objectives: This study aims to retrospectively evaluate pediatric Guillain-Barre syndrome cases in a tertiary center in Istanbul, Turkey. Materials and Methods: The data of 40 patients with Guillain-Barre syndrome who had been admitted to the Department of Pediatrics at the Istanbul University Medical Faculty between 2005 and 2011 were collected. Mann-Whitney U, Kruskal-Wallis, chi-square, and Fisher's exact tests were used for statistical analysis. Results: Mean patient age was 5.4 +/- 3.0 years; 20 out of 40 patients (50%) were female and 20 (50%) were male. Preceding infection was detected in 32 cases (80%). Six patients had speech impairment. Out of eight patients with respiratory distress (20%), five required respiratory support (12.5%) of which three of them had speech impairment as well. According to nerve conduction studies, 21 patients (52.5%) had acute inflammatory demyelinating polyradiculoneuropathy, 14 (35%) had acute motor axonal neuropathy, and five (12.5%) had acute motor-sensory axonal neuropathy. Thirty-three patients (82.5%) received intravenous immunglobulin, 3 (7.5%) underwent plasmapheresis and 4 (10%) received both. Time until recovery (P = 0.022) and time until aided (P = 0.036) and unaided (P = 0.027) walking were longer in patients with acute gastrointestinal infection than in those with upper respiratory tract infection (P < 0.05). Time until response to treatment (P = 0.001), time until aided (P = 0.001) and unaided (P = 0.002) walking, and time until complete recovery (P = 0.002) were longer in acute motor axonal neuropathy cases as compared to acute inflammatory demyelinating polyradiculoneuropathy cases. Conclusion: Recovery was longer with acute gastrointestinal infection and acute motor axonal neuropathy. Speech impairment could be a clinical clue for the need of mechanical ventilation. | |
dc.language.iso | eng | |
dc.subject | Nöroloji | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | KLİNİK NEUROLOJİ | |
dc.title | Pediatric Guillain-Barre syndrome: Indicators for a severe course | |
dc.type | Makale | |
dc.relation.journal | ANNALS OF INDIAN ACADEMY OF NEUROLOGY | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 18 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 24 | |
dc.identifier.endpage | 28 | |
dc.contributor.firstauthorID | 219197 | |