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Treatment of plasminogen deficiency patients with fresh frozen plasma

dc.contributor.authorChristiansen, Nina Merete
dc.contributor.authorÖZDAĞ, Hilal
dc.contributor.authorSchuster, Volker
dc.contributor.authorCelkan, Tiraje
dc.contributor.authorCokugras, Haluk
dc.contributor.authorKoc, Begum
dc.contributor.authorDikme, Gurcan
dc.contributor.authorKizilocak, Hande
dc.contributor.authorOzdemir, Nihal
dc.contributor.authorIskeleli, Guzin
dc.contributor.authorAtabek, Ayse Ayzit
dc.contributor.authorDonmez-Demir, Buket
dc.contributor.authorZiegler, Maike
dc.date.accessioned2021-03-06T09:29:55Z
dc.date.available2021-03-06T09:29:55Z
dc.date.issued2018
dc.identifier.citationKizilocak H., Ozdemir N., Dikme G., Koc B., Atabek A. A. , Cokugras H., Iskeleli G., Donmez-Demir B., Christiansen N. M. , Ziegler M., et al., "Treatment of plasminogen deficiency patients with fresh frozen plasma", PEDIATRIC BLOOD & CANCER, cilt.65, 2018
dc.identifier.issn1545-5009
dc.identifier.othervv_1032021
dc.identifier.otherav_e5dc150d-ff6f-4c6e-b399-346b98db2975
dc.identifier.urihttp://hdl.handle.net/20.500.12627/151212
dc.identifier.urihttps://doi.org/10.1002/pbc.26779
dc.description.abstractCongenital plasminogen (Plg) deficiency leads to the development of ligneous membranes on mucosal surfaces. Here, we report our experience with local and intravenous fresh frozen plasma (FFP). We retrospectively reviewed medical files of 17 patients and their eight first-degree relatives. Conjunctivitis was the main complaint. Thirteen patients were treated both with intravenous and conjunctival FFP. Venous thrombosis did not develop in any. Genetic evaluation revealed heterogeneous mutations as well as polymorphisms. Diagnosis and treatment of Plg deficiency is challenging; topical and intravenous FFP may be an alternative treatment.
dc.language.isoeng
dc.subjectİç Hastalıkları
dc.subjectONKOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectHEMATOLOJİ
dc.subjectPEDİATRİ
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectHematoloji
dc.subjectOnkoloji
dc.titleTreatment of plasminogen deficiency patients with fresh frozen plasma
dc.typeMakale
dc.relation.journalPEDIATRIC BLOOD & CANCER
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume65
dc.identifier.issue2
dc.contributor.firstauthorID251320


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