Association of HLA-DRB1*15 and HLA-DQB1*06 with SLE in Saudis
Tarih
2013Yazar
Sutton, Paul
Uyar, Aytul F.
Hajeer, Ali H.
Al-Motwee, Saleh
Jawdat, Dunia
Jehani, Ghassan S.
Anazi, Hanan
Shubaili, Abdullah
Üst veri
Tüm öğe kaydını gösterÖzet
BACKGROUND AND OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by humoral autoimmunity. The etiology of SLE is thought to be multifactorial including environmental, hormonal, and genetic factors. The human leukocyte antigen (HLA) has extensively been associated with the susceptibility to SLE; however, the association is heterogeneous among different ethnic groups. The aim of this study was to determine the association of HLA-A, HLA-B, HLA-DRB1, and HLA-DQB1 with SLE susceptibility in the Saudi population.
Koleksiyonlar
- Makale [92796]