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dc.contributor.authorBurcak, GÜLDEN
dc.contributor.authorInci, Ender
dc.contributor.authorKorkut, N
dc.contributor.authorCivelek, SABİHA
dc.contributor.authorSeven, Arzu Naciye
dc.contributor.authorInci, F
dc.date.accessioned2021-03-06T09:46:10Z
dc.date.available2021-03-06T09:46:10Z
dc.date.issued2003
dc.identifier.citationInci E., Civelek S., Seven A. N. , Inci F., Korkut N., Burcak G., "Laryngeal cancer: in relation to oxidative stress", TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, cilt.200, ss.17-23, 2003
dc.identifier.issn0040-8727
dc.identifier.othervv_1032021
dc.identifier.otherav_e716efad-40c5-407e-a460-6d23de2ea03e
dc.identifier.urihttp://hdl.handle.net/20.500.12627/151998
dc.identifier.urihttps://doi.org/10.1620/tjem.200.17
dc.description.abstractThis study was designed to investigate the oxidative stress parameters in laryngeal cancer and cancer-free adjacent tissues. Lipid peroxidation end product and the endogenous antioxidant components-CuZn superoxide dismutase (CuZnSOD) glutathione peroxidase (GSH Px), glutathione reductase (GSSG Rd) and glutathione (GSH)-were analysed by spectrophotometric and kinetic methods. Laryngeal cancer tissue exhibited higher lipid peroxidation than cancer free adjacent tissue. CuZn SOD and GSH Px activities and GSH level were significantly higher and GSSG Rd activity significantly lower in the cancer tissue. Detection of the antioxidant status may be useful to determine the tumour resistance to therapy, to choose the correct radiotherapy/chemotherapy and to monitor the effectiveness of the therapetic strategy.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, GENEL & İÇECEK
dc.titleLaryngeal cancer: in relation to oxidative stress
dc.typeMakale
dc.relation.journalTOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume200
dc.identifier.issue1
dc.identifier.startpage17
dc.identifier.endpage23
dc.contributor.firstauthorID2665


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