Prostate-specific antigen flare induced by cabazitaxel-based chemotherapy in patients with metastatic castration-resistant prostate cancer

Tarih
2014
Yazar
Delanoy, Nicolas
Ozguroglu, Mustafa
Rouge, Thibault de La Motte
Elaidi, Reza-Thierry
Oudard, Stephane
Angelergues, Antoine
Maillet, Denis
Flechon, Aude
Mercier, Florence
Guillot, Aline
Le Moulec, Sylvestre
Gravis, Gwenaelle
Beuzeboc, Philippe
Massard, Christophe
Fizazi, Karim
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Özet
Background: A prostate-specific antigen (PSA) flare occurs in about 15% of metastatic castration-resistant prostate cancer (mCRPC) patients receiving docetaxel. This flare has no standard definition. Its impact on treatment efficacy is unclear. We sought to evaluate the incidence and characteristics of PSA flare on cabazitaxel, and its impact on survival.
Bağlantı
http://hdl.handle.net/20.500.12627/154304
https://doi.org/10.1016/j.ejca.2014.03.015
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