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dc.contributor.authorAydin Canturk, Ilknur
dc.contributor.authorSaruhan Direskeneli, Guher
dc.contributor.authorYildiz Manukyan, Nuket
dc.contributor.authorCandan, Fatma
dc.contributor.authorUnsal Cakmak, Aysen
dc.contributor.authorIsik, Nihal
dc.date.accessioned2021-03-06T10:39:59Z
dc.date.available2021-03-06T10:39:59Z
dc.date.issued2014
dc.identifier.citationIsik N., Yildiz Manukyan N., Aydin Canturk I., Candan F., Unsal Cakmak A., Saruhan Direskeneli G., "Genetic Susceptibility to Multiple Sclerosis: The Role of FOXP3 Gene Polymorphism", NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.51, ss.69-73, 2014
dc.identifier.issn1300-0667
dc.identifier.otherav_eb787a37-a576-4192-8a37-cb675416840e
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/154638
dc.identifier.urihttps://doi.org/10.4274/npa.y7098
dc.description.abstractIntroduction: It is well recognized that both genetic and environmental factors play an important role in the pathogenesis of multiple sclerosis (MS). Immune pathogenesis of MS focuses on pathogenic CD4+ T lymphocytes. CD4+CD25+ regulatory T cells have suppressive function in this cell group. FOXP3 (forkhead boxP3) transcription factor is a key structure in the development and function of regulatory cells. Functional alterations in FOXP3 gene expression have been observed in various autoimmune diseases.
dc.language.isoeng
dc.subjectNöroloji
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.titleGenetic Susceptibility to Multiple Sclerosis: The Role of FOXP3 Gene Polymorphism
dc.typeMakale
dc.relation.journalNOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
dc.contributor.departmentIstanbul Goztepe Training and Research Hospital , ,
dc.identifier.volume51
dc.identifier.issue1
dc.identifier.startpage69
dc.identifier.endpage73
dc.contributor.firstauthorID212715


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