dc.contributor.author | Ozdemir, S | |
dc.contributor.author | Tabak, F | |
dc.contributor.author | Akdogan, M | |
dc.contributor.author | Ozturk, R | |
dc.contributor.author | Ozbay, G | |
dc.contributor.author | Senturk, H | |
dc.contributor.author | Mert, A | |
dc.contributor.author | Sander, E | |
dc.date.accessioned | 2021-03-02T22:56:40Z | |
dc.date.available | 2021-03-02T22:56:40Z | |
dc.identifier.citation | Senturk H., Mert A., Tabak F., Sander E., Akdogan M., Ozdemir S., Ozturk R., Ozbay G., "Treatment of chronic hepatitis B infection with IFN-alpha: Long term results and influence of delta superinfection", 10th Mediterranean Congress of Chemotherapy, Antalya, Türkiye, 20 - 25 Ekim 1996, ss.391-395 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_0f89556e-3b4a-425c-92be-97c1da0b9e82 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/15986 | |
dc.description.abstract | We aimed to evaluate the long-term effect of interferon-alfa(Ifh-alpha.) on chronic type B hepatitis. We treated 39 patients with Ifn-alpha 2a for 4-6 moths with various doses. The patients were followed-up for, at least, 18 months untreated:. Tell of 39(26%) were carrying antibodies against delta agent. In 14 of 29 delta negatives, HBeAg was present in circulation. The other 15 were HBV-DNA +ve, and HBeAg -ve. Five of 14(36%) HBe +ves, and 8 of 15(53%)HBe -ves responded. None of the 10 anti-delta +ves responded. 2/5(40%) from HBe + group, and 4/8(50%) from HBe -ve group relapsed. The overall sustained response rate was 21% in tile HBe +ve, and 27% in tile HBe -ve group. It was concluded that Ifn-alpha treatment achieves all overall sustained response rate of 24% in chronic type B hepatitis uncomplicated by delta agent. Patients with delta superinfection, invariably, do not respond to conventional treatment. | |
dc.language.iso | eng | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | İç Hastalıkları | |
dc.subject | Onkoloji | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Mikrobiyoloji | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | ONKOLOJİ | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.title | Treatment of chronic hepatitis B infection with IFN-alpha: Long term results and influence of delta superinfection | |
dc.type | Bildiri | |
dc.contributor.department | , , | |
dc.contributor.firstauthorID | 117031 | |