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Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats

dc.contributor.authorKandemir, Cansu
dc.contributor.authorKucukali, Cem Ismail
dc.contributor.authorBastaskin, Tugce
dc.contributor.authorŞİRVANCI, SERAP
dc.contributor.authorUTKAN, TİJEN
dc.contributor.authorTuzun, Erdem
dc.contributor.authorOzkartal, Ceren Sahin
dc.contributor.authorARICIOĞLU, FEYZA
dc.date.accessioned2021-03-06T12:36:37Z
dc.date.available2021-03-06T12:36:37Z
dc.date.issued2019
dc.identifier.citationARICIOĞLU F., Ozkartal C. S. , Bastaskin T., Tuzun E., Kandemir C., ŞİRVANCI S., Kucukali C. I. , UTKAN T., "Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats", CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, cilt.17, ss.261-272, 2019
dc.identifier.issn1738-1088
dc.identifier.otherav_f4abae42-78c9-488a-a225-383a135d2492
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/160382
dc.identifier.urihttps://doi.org/10.9758/cpn.2019.17.2.261
dc.description.abstractObjective: Purinergic 2X7 receptor (P2X7R) activation is known to be involved in pathogenesis of depression. Our aims were to investigate P2X7R-activated inflammasome pathways in parallel with induction of depression and to test the antidepressant-like effects of the selective P2X7R antagonist Brilliant Blue G (BBG) in a rat model of chronic unpredictable mild stress (CUMS).
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectSağlık Bilimleri
dc.subjectTemel Eczacılık Bilimleri
dc.subjectEczacılık
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSinirbilim ve Davranış
dc.subjectNEUROSCIENCES
dc.titleAntidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats
dc.typeMakale
dc.relation.journalCLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
dc.contributor.departmentİstanbul Üniversitesi , Deneysel Tıp Araştırma Enstitüsü , Sinirbilim Ad
dc.identifier.volume17
dc.identifier.issue2
dc.identifier.startpage261
dc.identifier.endpage272
dc.contributor.firstauthorID264054


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