The Effects of Exogenous Melatonin on Peripheral Nerve Regeneration and Collagen Formation in Rats
Date
2011Author
Buyukhatipoglu, Hakan
Erkutlu, Ibrahim
Bekerecioglu, Mehmet
Tercan, Mustafa
Pence, Sadrettin
ATİK, BEKİR
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Background. Peripheral nerve damage that requires surgical repair does not result in complete recovery because of collagen scar formation, ischemia, free oxygen radical damage, and other factors. To date, the best treatment method has not yet been determined. In this study, we designed an experimental peripheral nerve injury model, and researched the possible effects of melatonin hormone, based on evidence of its strong antioxidant and cell-protective effects via mimicking the effects of calcium channel blockers.
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