Show simple item record

dc.contributor.authorUnal, O. F.
dc.contributor.authorGÜR, DENİZ
dc.contributor.authorAkyol, U.
dc.contributor.authorHascelik, G.
dc.contributor.authorSENNAROĞLU, LEVENT
dc.contributor.authorESER, ÖZGEN
dc.contributor.authorIpci, K.
dc.contributor.authorALP, SUAT
dc.date.accessioned2021-03-06T19:58:39Z
dc.date.available2021-03-06T19:58:39Z
dc.date.issued2009
dc.identifier.citationESER Ö., Ipci K., ALP S., Akyol U., Unal O. F. , Hascelik G., SENNAROĞLU L., GÜR D., "Efficacy of nasopharyngeal culture in identification of pathogens in middle ear fluid in chronic otitis media with effusion", INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, cilt.27, ss.237-241, 2009
dc.identifier.issn0255-0857
dc.identifier.otherav_f89678f6-5257-4117-8b71-810372507d1f
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/162823
dc.identifier.urihttps://doi.org/10.4103/0255-0857.53206
dc.description.abstractPurpose: Chronic otitis media with effusion (OME) is the leading cause of hearing loss during childhood. In bacterial etiology of OME, the most frequent pathogens responsible are Haemophilus influenzae followed by Streptococcus pneumoniae and Moraxella catarrhalis . This study aimed at evaluating the accuracy of nasopharyngeal (NP) specimens in the identification of pathogens in the middle ear fluid (MEF) in patients with OME. Materials and Methods: In this cross sectional, case-control study, 95 MEFs and 53 NP secretion specimens were obtained from 53 children. As a control group, 102 NP specimens were taken from children having an operation other than an otological disease. Conventional culture methods and multiplex-PCR method have been used to determine the etiology of OME; NP carriage between cases and control groups were compared using conventional culture methods. Pearson Chi-Square and Fishers Exact tests were used in statistical analysis. Results : Bacteria were isolated by culture in 37.9 of MEF specimens, 14.7 of which belonged to the group H. influenzae , S. pneumoniae and M. catarrhalis. PCR was positive in 30.5 specimens targeting the same pathogens. There was a two-fold increase in carriage rate of S. pneumoniae and H. influenzae in patients than controls for each pathogen. Conclusion: PCR is a more reliable method to detect middle ear pathogens in MEF in comparison with the conventional culture methods. The NP colonization wasnt found to be an indicator of the pathogen in MEF although middle ear pathogens colonize more in nasopharynx of diseased children.
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectİmmünoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTemel Bilimler
dc.titleEfficacy of nasopharyngeal culture in identification of pathogens in middle ear fluid in chronic otitis media with effusion
dc.typeMakale
dc.relation.journalINDIAN JOURNAL OF MEDICAL MICROBIOLOGY
dc.contributor.departmentHacettepe Üniversitesi , Tıp Fakültesi (Türkçe) , Temel Tıp Bilimleri Bölümü
dc.identifier.volume27
dc.identifier.issue3
dc.identifier.startpage237
dc.identifier.endpage241
dc.contributor.firstauthorID307390


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record