Brain Infiltration of Immune Cells in CASPR2-Antibody Associated Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
Date
2016Author
Bilgic, Bilge
Unverengil, Gökçen
Kabadayi, Sevil
Tuzun, Erdem
Baykan, BETÜL
Erdag, Ece
Vanli Yavuz, Ebru Nur
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Introduction: Antibodies directed against neuronal surface antigens have recently been identified in patients with focal temporal lobe epilepsy (TLE) of unknown cause and mesial TLE with hippocampal sclerosis (MTLE-HS), thereby emphasizing the role of autoimmunity in TLE. Antibodies to contactin-associated protein-like 2 (CASPR2) are prevalent in MTLE-HS patients. We aimed to find out whether anti-neuronal autoimmunity might be involved in CASPR2 antibodyrelated MTLE-HS.
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