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dc.contributor.authorOncu, S
dc.contributor.authorEraksoy, H
dc.contributor.authorPunar, M
dc.date.accessioned2021-03-02T23:07:39Z
dc.date.available2021-03-02T23:07:39Z
dc.date.issued2004
dc.identifier.citationOncu S., Punar M., Eraksoy H., "Susceptibility patterns of enterococci causing infections", TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, cilt.202, sa.1, ss.23-29, 2004
dc.identifier.issn0040-8727
dc.identifier.otherav_10ab9f72-e3c9-4d63-bc31-85c654d5dd7b
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/16699
dc.identifier.urihttps://doi.org/10.1620/tjem.202.23
dc.description.abstractEnterococci are among the common organisms associated with hospital-acquired infections. We examined in vitro activities of different antibiotics to 103 enterococcal isolates. Minimal inhibitory concentrations (MICs) of penicillin G, ampicillin, gentamicin, ciprofloxacin, ofloxacin, levofloxacin, grepafloxacin, trovafloxacin and gemifloxacin were determined by broth microdilution testing method. Among the isolates 71 (69%) were identified as E. faecalis and 32 (31%) as E. faecium. While over 75% of E. faecium isolates were resistant to penicillin and ampicillin, approximately 25% of E. faecalis isolates were resistant to penicillin and ampicillin. None of the E. faecalis and E. faecium isolates were resistant to vancomycin. While 17 (52%) of E. faecium isolates exhibited high-level gentamicin resistance (HLGR), high level streptomycin resistance (HLSR) was detected in 24 (74%) of the isolates. In contrast, HLGR and HLSR rates for E. faecalis were 14 (20%) and 22 (31%), respectively. Both HLGR and HLSR were detected with higher frequency in ampicillin resistant isolates. Among fluoroquinolones, gemifloxacin and trovafloxacin were the most potent antibiotics tested. There was no increase in MIC90 values of the fluoroquinolones in ampicillin resistant isolates in comparison with ampicillin susceptible isolates. Our data suggest newer fluoroquinolones would be good alternative agents to use especially for combination drug therapy where enterococci with ampicillin resistance and HLAR are prevalent.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, GENEL & İÇECEK
dc.titleSusceptibility patterns of enterococci causing infections
dc.typeMakale
dc.relation.journalTOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
dc.contributor.department, ,
dc.identifier.volume202
dc.identifier.issue1
dc.identifier.startpage23
dc.identifier.endpage29
dc.contributor.firstauthorID170456


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