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dc.contributor.authorSumnu, Abdullah
dc.contributor.authorAydin, Zeki
dc.contributor.authorUzun, Sami
dc.contributor.authorCebeci, Egemen
dc.contributor.authorOzturk, Savaş
dc.contributor.authorKAZANCIOĞLU, Rümeyza
dc.contributor.authorGursu, Meltem
dc.contributor.authorKaradag, Serhat
dc.contributor.authorTatli, Emel
dc.date.accessioned2021-03-08T15:36:12Z
dc.date.available2021-03-08T15:36:12Z
dc.date.issued2012
dc.identifier.citationKAZANCIOĞLU R., Gursu M., Karadag S., Tatli E., Aydin Z., Uzun S., Sumnu A., Cebeci E., Ozturk S., "Volume Status in Patients on Peritoneal Dialysis: The Role of Apelin and Bio-Impedance Spectroscopy", RENAL FAILURE, cilt.34, sa.9, ss.1068-1073, 2012
dc.identifier.issn0886-022X
dc.identifier.othervv_1032021
dc.identifier.otherav_6d9e084e-eceb-4e1a-aaf1-0a88eb3feabd
dc.identifier.urihttp://hdl.handle.net/20.500.12627/167668
dc.identifier.urihttps://doi.org/10.3109/0886022x.2012.712860
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/6d9e084e-eceb-4e1a-aaf1-0a88eb3feabd/file
dc.description.abstractOne of the main factors determining the survival of peritoneal dialysis (PD) patients is volume status. We aimed to investigate hydration status of PD patients by bio-impedance spectroscopy (BIS) and echocardiography and to study the relation of them with apelin, which has effects related with volume status like vasodilation, positive inotropism, and inhibition of ADH release and RAS antagonism. Chronic PD patients without active cardiac disease or clinically prominent hypervolemia were included. Besides the demographic, clinical, and laboratory data, BIS and echocardiographic findings together with apelin levels were recorded. The study included 21 patients. Of them, eight patients were euvolemic, one patient was hypovolemic, and others have some degree of overhydration (1.1-6.8 L) with BIS, although all were euvolemic clinically. Mean apelin level was 1.49 +/- 0.49 ng/mL. Apelin level was positively correlated with ejection fraction and negatively with total body water (TBW), intracellular and extracellular water, lean tissue mass, and left atrium diameter. On linear regression model, TBW was the major determinant of apelin. Although apelin is expected to increase in hypervolemic patients, the negative correlation with body water in this study may be related with yet unknown role of apelin in dialyzed patients. They may have important roles in volume status in future.
dc.language.isoeng
dc.subjectUrology
dc.subjectHealth Sciences
dc.subjectÜROLOJİ VE NEFROLOJİ
dc.subjectNefroloji
dc.subjectİç Hastalıkları
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectNephrology
dc.titleVolume Status in Patients on Peritoneal Dialysis: The Role of Apelin and Bio-Impedance Spectroscopy
dc.typeMakale
dc.relation.journalRENAL FAILURE
dc.contributor.departmentBezmiâlem Vakıf Üniversitesi , Tıp Fakültesi , Dahili Tıp Bilimleri Bölümü
dc.identifier.volume34
dc.identifier.issue9
dc.identifier.startpage1068
dc.identifier.endpage1073
dc.contributor.firstauthorID2529025


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