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dc.contributor.authorAkkoc, Tolga
dc.contributor.authorArat, Sezen
dc.contributor.authorSAĞIRKAYA, HAKAN
dc.contributor.authorBagis, Haydar
dc.contributor.authorTaskin, Ali Cihan
dc.date.accessioned2021-12-10T10:18:27Z
dc.date.available2021-12-10T10:18:27Z
dc.date.issued2016
dc.identifier.citationTaskin A. C. , Akkoc T., SAĞIRKAYA H., Bagis H., Arat S., "Comparison of the development of mouse embryos manipulated with different biopsy techniques", TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, cilt.40, sa.2, ss.157-162, 2016
dc.identifier.issn1300-0128
dc.identifier.othervv_1032021
dc.identifier.otherav_37c4ed2f-fcb5-4724-8d67-cf273a32cc59
dc.identifier.urihttp://hdl.handle.net/20.500.12627/169632
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/37c4ed2f-fcb5-4724-8d67-cf273a32cc59/file
dc.identifier.urihttps://doi.org/10.3906/vet-1506-63
dc.description.abstractPreimplantation genetic diagnosis is the detection of inherited diseases and the sex of embryos before implantation in the practice of human medicine as well as in veterinary medicine. The introduction of experimental animal embryo biopsy techniques has been a milestone in the developmental process of preimplantation genetic diagnosis techniques. The aim of the present study was to evaluate in vivo and in vitro development of embryos after biopsy in an experimental mouse model and to perform comparisons across different biopsy techniques (blastomere biopsy and trophectoderm biopsy). At the end of the study, no significant difference was observed between the blastomere biopsy group and the control group in terms of in vitro development, embryo quality, and fetal development, whereas embryo quality and in vivo development were negatively affected in the trophectoderm biopsy group (P < 0.05).
dc.language.isoeng
dc.subjectSmall Animals
dc.subjectHealth Sciences
dc.subjectTarımsal Bilimler
dc.subjectEquine
dc.subjectVeterinary (miscellaneous)
dc.subjectGeneral Veterinary
dc.subjectVeteriner Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectBitki ve Hayvan Bilimleri
dc.subjectVETERİNERLİK BİLİMLERİ
dc.titleComparison of the development of mouse embryos manipulated with different biopsy techniques
dc.typeMakale
dc.relation.journalTURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES
dc.contributor.departmentKoç Üniversitesi , ,
dc.identifier.volume40
dc.identifier.issue2
dc.identifier.startpage157
dc.identifier.endpage162
dc.contributor.firstauthorID2742465


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